Transcription Factor

Accessions: Q8N859 (JASPAR 2024)
Names: ZN713_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q8N859
Length: 430
Pfam Domains: 19-59 KRAB box
268-283 Zinc-finger double domain
272-293 C2H2-type zinc finger
273-295 C2H2-type zinc finger
273-295 Zinc finger, C2H2 type
288-311 Zinc-finger double domain
301-323 C2H2-type zinc finger
301-323 Zinc finger, C2H2 type
301-321 C2H2-type zinc finger
316-340 Zinc-finger double domain
328-351 C2H2-type zinc finger
329-351 Zinc finger, C2H2 type
329-349 C2H2-type zinc finger
343-367 Zinc-finger double domain
356-379 C2H2-type zinc finger
357-379 Zinc finger, C2H2 type
357-379 C2H2-type zinc finger
371-395 Zinc-finger double domain
384-405 C2H2-type zinc finger
385-407 Zinc finger, C2H2 type
385-407 C2H2-type zinc finger
Sequence:
(in bold interface residues)
1 MEEEEMNDGSQMVRSQESLTFQDVAVDFTREEWDQLYPAQKNLYRDVMLENYRNLVALGY 60
61 QLCKPEVIAQLELEEEWVIERDSLLDTHPDGENRPEIKKSTTSQNISDENQTHEMIMERL 120
121 AGDSFWYSILGGLWDFDYHPEFNQENHKRYLGQVTLTHKKITQERSLECNKFAENCNLNS 180
181 NLMQQRIPSIKIPLNSDTQGNSIKHNSDLIYYQGNYVRETPYEYSECGKIFNQHILLTDH 240
241 IHTAEKPSECGKAFSHTSSLSQPQMLLTGEKPYKCDECGKRFSQRIHLIQHQRIHTGEKP 300
301 FICNGCGKAFRQHSSFTQHLRIHTGEKPYKCNQCGKAFSRITSLTEHHRLHTGEKPYECG 360
361 FCGKAFSQRTHLNQHERTHTGEKPYKCNECGKAFSQSAHLNQHRKIHTREKLCEYKCEQT 420
421 VRHSPSFSST
Interface Residues: 198, 201, 204, 205, 207, 208, 211, 214, 233, 234, 235, 236, 239, 256, 258, 259, 262, 283, 284, 286, 287, 290, 294, 301, 312, 313, 314, 315, 317, 318, 320, 321, 322, 324, 339, 340, 341, 342, 343, 344, 345, 346, 367, 368, 369, 370, 371, 373, 374, 375, 395, 396, 397, 398, 399, 400, 401, 402, 403
3D-footprint Homologues: 8ssu_A, 8ssq_A, 5v3j_F, 5yel_A, 1tf6_A, 2i13_A, 7w1m_H, 6jnm_A, 5und_A, 5kkq_D, 5ei9_F, 5kl3_A, 6wmi_A, 6a57_A, 2kmk_A, 2gli_A, 6ml4_A, 6blw_A, 7txc_E, 5k5i_A, 7eyi_G, 6e94_A, 7ysf_A, 2jpa_A, 1ubd_C, 7y3l_A, 7n5w_A, 1tf3_A, 1g2f_F, 5k5l_F, 4x9j_A, 8gn3_A, 6u9q_A, 1mey_C, 2drp_D, 1f2i_J, 8h9h_G, 2lt7_A, 8cuc_F, 3uk3_C, 1llm_D, 2wbs_A, 4m9v_C, 7y3m_I, 5yj3_D
Binding Motifs: UN0217.1 tmGACGACTGCCACGAAAs
UN0216.1 taGAAAAAAGACwrGAAAg
UN0216.2 aGAAAAAAGACwrGAAA
UN0217.2 mGACGACTGCCACGAAA
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.