Transcription Factor
| Accessions: | T060519_1.02 (CISBP 1.02), Q9VWC6 (JASPAR 2024) |
| Names: | T060519_1.02;, vfl, FI17950p1, Q9VWC6_DROME, Zelda, isoform A, Zelda, isoform B, Zelda, isoform G |
| Organisms: | Drosophila melanogaster |
| Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | experiment type:B1H, family:C2H2 ZF |
| Length: | 1596 |
| Pfam Domains: | 281-303 C2H2-type zinc finger 552-573 C2H2-type zinc finger 552-577 Zinc-finger double-stranded RNA-binding 552-572 Zinc-finger of C2H2 type 1341-1364 Zinc-finger double domain 1355-1377 C2H2-type zinc finger 1384-1407 C2H2-type zinc finger 1398-1422 Zinc-finger double domain 1413-1435 Zinc finger, C2H2 type 1415-1436 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MTSIKTEMPPLHAAEALASSSATDSGGGGAGGGGGGGGGGSGGPGAGGTGGVGSAPATPN 60 61 ATISAAADSSDNQPGTPQPTQQQQSTQQQLQQPQSQQQQQQAMGGGDPQQQQQQQQVTGI 120 121 THQPYATHHMYSASGGQQQQQQQIYGGLYGGDMQQQQGYASSYINSYEQFYQQQQQQQQG 180 181 TDYAFGTVGVDYGKSAGVRYHPYLQTPTSGLGGIPTASSAQEEAGSAPSAVSTTTAVAMS 240 241 PRVVSSSSPTSTSSHLQLGSSSGQTPGSPGGAAGSAGCKLQCKKCGILTTNESELQEHIA 300 301 NVHGESPYGSSGYASSPYIKEEMPTPQPPGVGSATANPGELLDLDSQKMVYHQQLLQQQQ 360 361 QQHDVVAGLPLGALPDPLHSMQSMQQRALHSWEQQPQQTVASVEGLPPYMQQGLGVGLGV 420 421 GVDKSPYYSPKQSPYHQSTGVGGATLIKQEYGGHGLIKSEYPDSQHYVDKSFDPTAGGAG 480 481 GAELCASVATSPAEFPSTTTGGPGQEGAAGAAPGGGYRGFEPPSSSSVLPANSLTAKAAT 540 541 WKSNEARRPKTYNCTACNKWFTSSGHLKRHYNTTLHKNAVKSSGQPDPATLPISAHHHPA 600 601 RDPVTKPSRRGNAAAAAAAAAAAASASGQGQQQQPPIPPPPANVPPPEPPRSPPDYGGGG 660 661 GLGVGAMGGAAMSQYSASPSPTQQQQHHLNHHQQQANGYANGTANGYGYMQQQVQSTTNA 720 721 SPQHASNNNSNNQQQQQQQQQHHQQQMPQHHNSVLNGHPNGLAGPSAPHNNNTTQMPSSQ 780 781 MRGLLNETTTTPPPTTTTRAPQITTTATTTTTAATTVAIKSEQMEDSNHTHTHTHTHPNH 840 841 SHSQDRSHSSSSSSSMATEEAEEQELRDQEQADDHLHQHQQASQQYLLSARHYHSSTPNT 900 901 LSSSNTNPSTPSSNSPHTIYRQEQQGTDFSRTTPPPQPLPPMGMLPPMAMDYNMLALDMP 960 961 MPMPTLMHSNMLQCSSTSTTPLATTITTSMPDTMQPPQQQLVHHYQAVLHPLHQQLGEQH 1020 1021 QRQEADHHQQQRELHQLDQQQQQQQALILADSLPHSSSSPTSSSPPPTMPMPLTTITAPQ 1080 1081 LLPLQPPPPHITSTMPMPPTMHMPIMPPPPQCYQQLQPLDPTMSYHTIIGSGPEAHTGTA 1140 1141 GGGYSNQITTSDGQILQLMPTSLFAPYAPLSPYSVAAQRSPQEGDLPPVHTLTTALHAHQ 1200 1201 QGGQQEAQTPTLTVLSTPYSPTVSSSRATPALEMDMATLMQHHQDYEMEQYQMQHQQLDQ 1260 1261 MQQHQQQLDHQQQQQILADQTQTMAQQPLAKKRRGGNATPSTTKRRRNSSVGSTSPHSTT 1320 1321 LPSGRIKCLECDKEFTKNCYLTQHNKSFHSGEYPFRCQKCGKRFQSEDVYTTHLGRHRTQ 1380 1381 DKPHKCELCPKQFHHKTDLRRHVEAIHTGLKQHMCDICEKGFCRKDHLRKHLETHNRPRV 1440 1441 VGKKSAAAAAAAAAAAAVTATAGLGGAPAAGSIKAAFARSLTVTAVSSEPGAGVAIPSAP 1500 1501 ATATCAPVSVSASALVQAVNPSLTSGLSLKRHIDDVAVDDDSLLEEDEDEMEMEMEMDML 1560 1561 EEEDEEEEELGDHHMIIKSEYVQEEFQMIEKSIELY |
| Interface Residues: | 1336, 1337, 1338, 1339, 1340, 1342, 1343, 1345, 1346, 1347, 1350, 1355, 1365, 1366, 1367, 1368, 1369, 1370, 1371, 1372, 1373, 1376, 1394, 1395, 1396, 1397, 1398, 1399, 1400, 1401, 1402, 1405, 1423, 1424, 1425, 1426, 1427, 1428, 1429, 1430, 1431 |
| 3D-footprint Homologues: | 5v3j_F, 1tf3_A, 7n5w_A, 5und_A, 1ubd_C, 5ei9_F, 8ssq_A, 7w1m_H, 5kkq_D, 8ssu_A, 6ml4_A, 1tf6_A, 6u9q_A, 8h9h_G, 7eyi_G, 7ysf_A, 6wmi_A, 2lt7_A, 2i13_A, 7y3m_I, 2jpa_A, 2kmk_A, 3uk3_C, 1mey_C, 2drp_D, 5yel_A, 2gli_A, 1g2f_F, 5kl3_A, 4x9j_A, 1llm_D, 6e94_A, 6blw_A, 8cuc_F, 7y3l_A, 2wbs_A, 7txc_E, 1f2i_J, 8gn3_A, 4m9v_C, 5yj3_D |
| Binding Motifs: | M5265_1.02 gCAGGTAG MA1462.1 htgCAGGTAgrh MA1462.2 CAGGTAg |
| Binding Sites: | MA1462.1.1 MA1462.1.10 MA1462.1.11 MA1462.1.12 MA1462.1.13 MA1462.1.14 MA1462.1.15 MA1462.1.16 MA1462.1.17 MA1462.1.18 MA1462.1.19 MA1462.1.2 MA1462.1.20 / MA1462.1.9 MA1462.1.3 MA1462.1.4 MA1462.1.5 MA1462.1.6 MA1462.1.7 MA1462.1.8 MA1462.2.1 / MA1462.2.15 / MA1462.2.3 / MA1462.2.5 MA1462.2.12 / MA1462.2.17 / MA1462.2.19 MA1462.2.10 / MA1462.2.11 / MA1462.2.16 / MA1462.2.18 / MA1462.2.20 / MA1462.2.6 / MA1462.2.7 / MA1462.2.9 MA1462.2.13 MA1462.2.14 MA1462.2.2 / MA1462.2.4 MA1462.2.8 |
| Publications: | Harrison MM, Li XY, Kaplan T, Botchan MR, Eisen MB. Zelda binding in the early Drosophila melanogaster embryo marks regions subsequently activated at the maternal-to-zygotic transition. PLoS Genet : (2011). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.