Transcription Factor

						

			
Accessions: T134143_1.02 (CISBP 1.02)

			
Names: nhr-36, T134143_1.02;
Organisms: Caenorhabditis elegans
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:Nuclear receptor
Length: 562
Pfam Domains:    35-106 Zinc finger, C4 type (two domains)
  238-411 Ligand-binding domain of nuclear hormone receptor
  437-553 Serpentine type 7TM GPCR chemoreceptor Srh
Sequence: 
(in bold interface residues)		   1 MSLSEGEDDPCSSSSIYDMSLYGNFAEKSEMSNEMCRVCGKNSAGKHYSVPACHGCKSFF   60
  61 RRAIIHKTAYPECKYDKMCFSKISRITRPRKCRYCRLQKCYEVGMVAIVAMHRKHDDSPL  120
 121 RSSDSELPDLPLPSPIATRENYVSGIIDKLHSLDIQTDKFRKSAYNPLFIPNLEGILASP  180
 181 GKLALADKYGAMPGWPLTQESFNEQQILMNQVNGDVLTDSSSSFVLPTADTPGINTKDWL  240
 241 GFDMLTAIEYAKTFPFFQQLESNDKILLTKATTFMNLALTSNYSSFLSKMAVLQMPDGIC  300
 301 ISGPVGQGEHEIRSFERRLSLRIMAPLIRNLFDRTEYVLLKAIILCNHAVTDLSCAAQNI  360
 361 LTRERHNFTGALLLYCLSRHGSHAGPARYYSIINMIDVLEHYQRDFRDFMLLLDISLPTR  420
 421 FAKHRKFLQREILNINVVCMVAISIILCPIFYLPMYGYQSNGLFRFVDWNLALPAIFTVY  480
 481 CILGVVISVMDLFHYRLKAILTMNTKPRNLKIKRFVQQLIYLAYTVLVFTAVSYLGLLKI  540
 541 QSSQDAIKPLVFEVSKLTAFWF
Interface Residues: 44, 45, 47, 48, 54, 55, 57, 58, 61, 62, 90, 114, 124, 126
3D-footprint Homologues: 6fbq_A, 6l6q_B, 7wnh_D, 1lo1_A, 3g9m_B, 1a6y_A, 4oln_B, 2ff0_A, 1dsz_A, 4umm_E, 3cbb_A, 7xvn_C, 4iqr_B, 2han_A, 1hcq_E, 8cef_H, 5krb_G, 2han_B, 1kb2_B, 2a66_A, 8hbm_B, 2nll_B, 1lat_A, 7xv6_B, 4hn5_B, 8rm6_A, 5emc_A, 7prw_B, 5cbx_B, 3g6t_A, 1r4i_A, 5cbz_E, 4tnt_B, 5e69_A
Binding Motifs: M1460_1.02 wwTGcttysr
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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