Transcription Factor

						

			
Accessions: 1per_L (3D-footprint 20231221), 1per_R (3D-footprint 20231221), 1rpe_L (3D-footprint 20231221), 1rpe_R (3D-footprint 20231221), 2or1_L (3D-footprint 20231221), 2or1_R (3D-footprint 20231221)

			
Names: 434 REPRESSOR, Fragment, Repressor protein CI, RPC1_BP434
Organisms: Phage 434
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P16117
Length: 63
Pfam Domains:      4-62 Helix-turn-helix domain
     4-57 Helix-turn-helix domain
     6-59 Helix-turn-helix
Sequence: 
(in bold interface residues)		   1 SISSRVKSKRIQLGLNQAELAQKVGTTQQSIEQLENGKTKRPRFLPELASALGVSVDWLL   60
  61 NGT
Interface Residues: 17, 18, 27, 28, 29, 30, 32, 33, 36, 38, 39, 43
3D-footprint Homologues: 7jvt_D, 3bdn_A, 3cro_R, 1per_L, 3zkc_A, 4z5h_A, 5k98_B, 3dnv_B, 6chv_D, 7tz1_A, 1rio_A
Binding Motifs: 2or1_L TACAAnAnA
1per_L tACaA
1per_LR tACaAgwwarnvtGTa
1rpe_L TTTTT
1rpe_LR AAmAAgnnnnATTGTA
2or1_LR TACAAnnTnTnTTGTA
Binding Sites: 1per_A
1per_B
1rpe_A
1rpe_B
2or1_A
2or1_B
			
Publications: Rodgers D.W, Harrison S.C. The complex between phage 434 repressor DNA-binding domain and operator site OR3: structural differences between consensus and non-consensus half-sites. Structure (London, England : 1993) 1:227-40 (1993). [Pubmed]


Shimon L.J, Harrison S.C. The phage 434 OR2/R1-69 complex at 2.5 A resolution. Journal of molecular biology 232:826-38 (1993). [Pubmed]


Aggarwal A.K, Rodgers D.W, Drottar M, Ptashne M, Harrison S.C. Recognition of a DNA operator by the repressor of phage 434: a view at high resolution. Science (New York, N.Y.) 242:899-907 (1988). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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