Transcription Factor
| Accessions: | P52740 (JASPAR 2024) |
| Names: | ZN132_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | P52740 |
| Length: | 706 |
| Pfam Domains: | 38-78 KRAB box 128-151 Zinc-finger double domain 141-151 C2H2-type zinc finger 235-249 C2H2-type zinc finger 236-258 Zinc finger, C2H2 type 283-302 Zinc-finger double domain 290-313 C2H2-type zinc finger 291-313 C2H2-type zinc finger 291-313 Zinc finger, C2H2 type 306-330 Zinc-finger double domain 319-339 C2H2-type zinc finger 337-358 Zinc-finger double domain 346-369 C2H2-type zinc finger 347-369 C2H2-type zinc finger 347-369 Zinc finger, C2H2 type 361-385 Zinc-finger double domain 375-397 C2H2-type zinc finger 375-397 Zinc finger, C2H2 type 375-397 C2H2-type zinc finger 389-414 Zinc-finger double domain 402-423 C2H2-type zinc finger 403-425 C2H2-type zinc finger 403-425 Zinc finger, C2H2 type 419-442 Zinc-finger double domain 430-453 C2H2-type zinc finger 431-453 C2H2-type zinc finger 431-453 Zinc finger, C2H2 type 445-469 Zinc-finger double domain 459-481 C2H2-type zinc finger 459-481 Zinc finger, C2H2 type 459-481 C2H2-type zinc finger 473-498 Zinc-finger double domain 487-509 Zinc finger, C2H2 type 487-509 C2H2-type zinc finger 487-509 C2H2-type zinc finger 504-526 Zinc-finger double domain 514-533 C2H2-type zinc finger 515-537 C2H2-type zinc finger 515-537 Zinc finger, C2H2 type 531-554 Zinc-finger double domain 542-565 C2H2-type zinc finger 543-565 C2H2-type zinc finger 543-565 Zinc finger, C2H2 type 560-581 Zinc-finger double domain 570-593 C2H2-type zinc finger 571-593 C2H2-type zinc finger 571-593 Zinc finger, C2H2 type 588-609 Zinc-finger double domain 598-610 C2H2-type zinc finger 599-621 C2H2-type zinc finger 599-621 Zinc finger, C2H2 type 617-638 Zinc-finger double domain 626-650 C2H2-type zinc finger 627-649 C2H2-type zinc finger 627-649 Zinc finger, C2H2 type 641-665 Zinc-finger double domain 654-677 C2H2-type zinc finger 655-677 C2H2-type zinc finger 655-677 Zinc finger, C2H2 type 670-694 Zinc-finger double domain 682-703 C2H2-type zinc finger 683-705 C2H2-type zinc finger 683-705 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MALPSPQVLMGLPALLMGPAQHTSWPCGSAVPTLKSMVTFEDVAVYFSQEEWELLDAAQR 60 61 HLYHSVMLENLELVTSLGSWHGVEGEGAHPKQNVSVEVLQVRIPNADPSTKKANSCDMCG 120 121 PFLKDILHLAEHQGTQSEEKPYTCGACGRDFWLNANLHQHQKEHSGGKPFRWYKDRDALM 180 181 KSSKVHLSENPFTCREGGKVILGSCDLLQLQAVDSGQKPYSNLGQLPEVCTTQKLFECSN 240 241 CGKAFLKSSTLPNHLRTHSEEIPFTCPTGGNFLEEKSILGNKKFHTGEIPHVCKECGKAF 300 301 SHSSKLRKHQKFHTEVKYYECIACGKTFNHKLTFVHHQRIHSGERPYECDECGKAFSNRS 360 361 HLIRHEKVHTGERPFECLKCGRAFSQSSNFLRHQKVHTQVRPYECSQCGKSFSRSSALIQ 420 421 HWRVHTGERPYECSECGRAFNNNSNLAQHQKVHTGERPFECSECGRDFSQSSHLLRHQKV 480 481 HTGERPFECCDCGKAFSNSSTLIQHQKVHTGQRPYECSECRKSFSRSSSLIQHWRIHTGE 540 541 KPYECSECGKAFAHSSTLIEHWRVHTKERPYECNECGKFFSQNSILIKHQKVHTGEKPYK 600 601 CSECGKFFSRKSSLICHWRVHTGERPYECSECGRAFSSNSHLVRHQRVHTQERPYECIQC 660 661 GKAFSERSTLVRHQKVHTRERTYECSQCGKLFSHLCNLAQHKKIHT |
| Interface Residues: | 303, 305, 307, 312, 316, 318, 329, 330, 332, 333, 335, 336, 358, 360, 361, 364, 385, 386, 387, 388, 389, 391, 392, 413, 414, 415, 416, 417, 419, 420, 421, 422, 423, 424, 426, 441, 442, 443, 444, 445, 446, 448, 449, 469, 470, 471, 472, 473, 475, 476, 479, 497, 498, 499, 500, 501, 503, 504, 526, 527, 528, 529, 532, 535, 543, 553, 554, 555, 556, 557, 559, 560, 566, 580, 581, 582, 583, 584, 585, 588, 592, 609, 610, 611, 612, 613, 615, 616, 637, 638, 639, 640, 641, 642, 644, 648, 665, 666, 667, 668, 669, 671, 672 |
| 3D-footprint Homologues: | 6dnw_A, 8gn3_A, 2lt7_A, 5k5i_A, 7w1m_H, 2drp_D, 6wmi_A, 7ysf_A, 8cuc_F, 7y3l_A, 5k5l_F, 8ssq_A, 1tf6_A, 4x9j_A, 5kkq_D, 8ssu_A, 4m9v_C, 6e94_A, 2jpa_A, 1ubd_C, 1tf3_A, 5kl3_A, 6u9q_A, 1f2i_J, 5und_A, 1g2f_F, 2wbs_A, 6ml4_A, 5yj3_D, 5v3j_F, 2i13_A, 1llm_D, 6blw_A, 7n5w_A, 6jnm_A, 8h9h_G, 7eyi_G, 6a57_A, 5yel_A, 2kmk_A, 5ei9_F, 3uk3_C, 1mey_C, 7txc_E, 2gli_A, 7y3m_I |
| Binding Motifs: | UN0596.1 GGrrrswGGGAAGGa UN0596.2 GGrrrswGGGAAGG |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.