Transcription Factor

Accessions: T134655_1.02 (CISBP 1.02)
Names: nhr-204, T134655_1.02;
Organisms: Caenorhabditis elegans
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:Nuclear receptor
Length: 441
Pfam Domains: 50-120 Zinc finger, C4 type (two domains)
244-415 Ligand-binding domain of nuclear hormone receptor
Sequence:
(in bold interface residues)
1 MLEYDQVELPSCSSASATSSPALESFIEQKPPKTKSLRKSGKPYQFVPSACQVCYGKATG 60
61 HHYDVASCNGCKSFFRRVTIEKLKYRCSAGNACYTNFGPGDPVPKCRACRYKRCLEAGMN 120
121 ALGIQSELRKHSENQPLEENSSEFGKEIVVLPRIKEPPKSIEAQVTDLINHLMHLDLKIT 180
181 TFRDCTYNPMSFPTLKQAIKNEVSIIGLGDRLGPMPGWPLSPETIEASRKPNPNPGSPRI 240
241 LPPNVKKWFSYDLLTVVEMAKTFDFFKKLSENDRFFLCRDTSLMVSNLMRAYFSVENKTD 300
301 KFIRADGQTFVPPPKIPKEYMDNLSSDIMMRAIKTLIRLACTKVEYLFLRAILLCNSAAP 360
361 DISASGRNILSTERAKYTVALLNYTMTHHGAAGPGRFAEILNVIDVLERQQKDQRDVNVY 420
421 ITLYRPKHVKLALFDDIMLTC
Interface Residues: 59, 60, 62, 63, 69, 70, 72, 73, 76, 77, 101, 128, 130, 133, 198, 200, 201, 202, 203
3D-footprint Homologues: 6fbq_A, 7wnh_D, 6l6q_B, 3g9m_B, 1a6y_A, 1lo1_A, 4oln_B, 5krb_G, 2han_B, 1kb2_B, 2a66_A, 8cef_H, 2nll_B, 1lat_A, 7xv6_B, 2ff0_A, 1dsz_A, 8hbm_B, 4umm_E, 3cbb_A, 7xvn_C, 4iqr_B, 2han_A, 1hcq_E, 5cbz_E, 4tnt_B, 5e69_A, 4hn5_B, 5emc_A, 8rm6_A, 7prw_B, 5cbx_B, 3g6t_A, 1r4i_A, 8c59_A
Binding Motifs: M1476_1.02 wwtTGrTmhv
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.