Transcription Factor
| Accessions: | Q9HCX3 (JASPAR 2024) |
| Names: | KRAB-containing zinc finger protein, Zinc finger protein 304, ZN304_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q9HCX3 |
| Length: | 659 |
| Pfam Domains: | 14-54 KRAB box 120-140 C2H2-type zinc finger 266-289 Zinc-finger double domain 279-301 Zinc finger, C2H2 type 293-318 Zinc-finger double domain 307-329 C2H2-type zinc finger 307-329 C2H2-type zinc finger 307-329 Zinc finger, C2H2 type 322-345 Zinc-finger double domain 335-357 C2H2-type zinc finger 335-357 Zinc finger, C2H2 type 337-355 C2H2-type zinc finger 349-374 Zinc-finger double domain 362-385 C2H2-type zinc finger 363-385 Zinc finger, C2H2 type 363-385 C2H2-type zinc finger 378-401 Zinc-finger double domain 390-409 C2H2-type zinc finger 391-413 Zinc finger, C2H2 type 391-413 C2H2-type zinc finger 406-430 Zinc-finger double domain 418-441 C2H2-type zinc finger 419-441 Zinc finger, C2H2 type 419-441 C2H2-type zinc finger 434-457 Zinc-finger double domain 447-466 C2H2-type zinc finger 447-469 C2H2-type zinc finger 462-486 Zinc-finger double domain 474-495 C2H2-type zinc finger 475-497 Zinc finger, C2H2 type 475-497 C2H2-type zinc finger 490-514 Zinc-finger double domain 502-523 C2H2-type zinc finger 503-525 Zinc finger, C2H2 type 503-525 C2H2-type zinc finger 517-542 Zinc-finger double domain 530-553 C2H2-type zinc finger 531-553 C2H2-type zinc finger 531-553 Zinc finger, C2H2 type 548-568 Zinc-finger double domain 559-581 C2H2-type zinc finger 559-581 Zinc finger, C2H2 type 559-581 C2H2-type zinc finger 573-597 Zinc-finger double domain 586-609 C2H2-type zinc finger 587-609 C2H2-type zinc finger 587-609 Zinc finger, C2H2 type 605-625 Zinc-finger double domain 615-637 Zinc finger, C2H2 type 615-637 C2H2-type zinc finger 615-637 C2H2-type zinc finger 629-646 Zinc-finger double domain |
| Sequence: (in bold interface residues) | 1 MAAAVLMDRVQSCVTFEDVFVYFSREEWELLEEAQRFLYRDVMLENFALVATLGFWCEAE 60 61 HEAPSEQSVSVEGVSQVRTAESGLFQKAHPCEMCDPLLKDILHLAEHQGSHLTQKLCTRG 120 121 LCRRRFSFSANFYQHQKQHNGENCFRGDDGGASFVKSCTVHMLGRSFTCREEGMDLPDSS 180 181 GLFQHQTTYNRVSPCRRTECMESFPHSSSLRQHQGDYDGQMLFSCGDEGKAFLDTFTLLD 240 241 SQMTHAEVRPFRCLPCGNVFKEKSALINHRKIHSGEISHVCKECGKAFIHLHHLKMHQKF 300 301 HTGKRHYTCSECGKAFSRKDTLVQHQRVHTGERSYDCSECGKAYSRSSHLVQHQRIHTGE 360 361 RPYKCNKCGKAFSRKDTLVQHQRFHTGERPYECSECGKFFSQSSHLIEHWRIHTGARPYE 420 421 CIECGKFFSHNSSLIKHRRVHTGARSYVCSKCGKAFGCKDTLVQHQIIHTGARPYECSEC 480 481 GKAFSRKDTLVQHQKIHTGERPYECGECGKFFSHSSNLIVHQRIHTGAKPYECNECGKCF 540 541 SHNSSLILHQRVHTGARPYVCSECGKAYISSSHLVQHKKVHTGARPYECSECGKFFSRNS 600 601 GLILHQRVHTGEKPYVCSECGKAYSRSSHLVRHQKAHTGERAHECNSFGGPLAASLKLV |
| Interface Residues: | 290, 292, 293, 296, 318, 320, 321, 324, 328, 335, 345, 346, 347, 348, 349, 351, 352, 354, 355, 356, 358, 373, 374, 375, 376, 377, 380, 383, 402, 403, 404, 405, 407, 408, 412, 430, 431, 432, 433, 435, 436, 458, 460, 461, 463, 464, 485, 486, 487, 488, 489, 492, 514, 515, 516, 517, 520, 521, 523, 541, 542, 543, 544, 545, 546, 547, 548, 549, 554, 568, 569, 570, 571, 572, 573, 576, 580, 597, 598, 599, 600, 601, 602, 604, 625, 626, 627, 628, 629, 631, 632, 655, 656 |
| 3D-footprint Homologues: | 6wmi_A, 1tf6_A, 4x9j_A, 5kkq_D, 6u9q_A, 2gli_A, 7ysf_A, 2kmk_A, 7n5w_A, 5k5l_F, 8ssu_A, 6ml4_A, 2drp_D, 8ssq_A, 7w1m_H, 5und_A, 8h9h_G, 2jpa_A, 6jnm_A, 2wbs_A, 7txc_E, 1f2i_J, 5v3j_F, 5yj3_D, 8gn3_A, 2lt7_A, 2i13_A, 5k5i_A, 7eyi_G, 6e94_A, 5yel_A, 1g2f_F, 4m9v_C, 5ei9_F, 7y3m_I, 1ubd_C, 6blw_A, 1mey_C, 5kl3_A, 6a57_A, 7y3l_A, 3uk3_C, 1tf3_A, 8cuc_F, 1llm_D |
| Binding Motifs: | UN0176.1 sTCATCTGAAGGCTyrACTGGGGm |
| Binding Sites: | UN0176.1.1 UN0176.1.10 / UN0176.1.8 UN0176.1.11 / UN0176.1.9 UN0176.1.10 / UN0176.1.12 UN0176.1.11 / UN0176.1.13 UN0176.1.12 / UN0176.1.14 UN0176.1.13 / UN0176.1.15 UN0176.1.14 / UN0176.1.16 UN0176.1.15 / UN0176.1.17 UN0176.1.16 / UN0176.1.18 UN0176.1.17 / UN0176.1.19 UN0176.1.1 / UN0176.1.2 UN0176.1.18 / UN0176.1.20 UN0176.1.3 UN0176.1.2 / UN0176.1.4 UN0176.1.3 / UN0176.1.5 UN0176.1.4 / UN0176.1.6 UN0176.1.5 / UN0176.1.7 UN0176.1.6 / UN0176.1.8 UN0176.1.7 / UN0176.1.9 UN0176.1.19 UN0176.1.20 |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.