Transcription Factor

						

			
Accessions: 1ozj_B (3D-footprint 20231221)

			
Names: hMAD-3, hSMAD3, JV15-2, MAD homolog 3, Mothers against decapentaplegic homolog 3, Mothers against DPP homolog 3, SMAD 3, SMAD family member 3, SMAD3_HUMAN
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P84022
Length: 124
Pfam Domains:    23-123 MH1 domain
Sequence: 
(in bold interface residues)		   1 PPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIP   60
  61 RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQ  120
 121 RVET
Interface Residues: 23, 25, 29, 64, 66, 68, 71, 73
3D-footprint Homologues: 8cli_A, 6fzs_A, 6h3r_A, 5nm9_A, 5od6_A, 5mey_A, 2qnf_A
Binding Motifs: 1ozj_AB GtCTAGaCA
1ozj_B AGaC
Binding Sites: 1ozj_C
1ozj_D
			
Publications: Chai J, Wu J.W, Yan N, Massagué J, Pavletich N.P, Shi Y. Features of a Smad3 MH1-DNA complex. Roles of water and zinc in DNA binding. The Journal of biological chemistry 278:20327-31 (2003). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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