Transcription Factor
Accessions: | 1ozj_B (3D-footprint 20231221) |
Names: | hMAD-3, hSMAD3, JV15-2, MAD homolog 3, Mothers against decapentaplegic homolog 3, Mothers against DPP homolog 3, SMAD 3, SMAD family member 3, SMAD3_HUMAN |
Organisms: | Homo sapiens |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Uniprot: | P84022 |
Length: | 124 |
Pfam Domains: | 23-123 MH1 domain |
Sequence: (in bold interface residues) | 1 PPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIP 60 61 RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQ 120 121 RVET |
Interface Residues: | 23, 25, 29, 64, 66, 68, 71, 73 |
3D-footprint Homologues: | 8cli_A, 6fzs_A, 5nm9_A, 5od6_A, 6h3r_A, 5mey_A, 2qnf_A |
Binding Motifs: | 1ozj_AB GtCTAGaCA 1ozj_B AGaC |
Binding Sites: | 1ozj_C 1ozj_D |
Publications: | Chai J, Wu J.W, Yan N, Massagué J, Pavletich N.P, Shi Y. Features of a Smad3 MH1-DNA complex. Roles of water and zinc in DNA binding. The Journal of biological chemistry 278:20327-31 (2003). [Pubmed] |
Related annotations: | PaperBLAST |
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