Transcription Factor
| Accessions: | Q86YE8 (JASPAR 2024) |
| Names: | ZN573_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q86YE8 |
| Length: | 665 |
| Pfam Domains: | 28-68 KRAB box 133-155 C2H2-type zinc finger 152-172 Zinc-finger double domain 161-184 C2H2-type zinc finger 162-184 C2H2-type zinc finger 162-184 Zinc finger, C2H2 type 177-200 Zinc-finger double domain 189-212 C2H2-type zinc finger 190-212 C2H2-type zinc finger 190-212 Zinc finger, C2H2 type 205-227 Zinc-finger double domain 217-227 C2H2-type zinc finger 218-240 Zinc finger, C2H2 type 235-256 Zinc-finger double domain 245-256 C2H2-type zinc finger 246-268 Zinc finger, C2H2 type 246-268 C2H2-type zinc finger 260-285 Zinc-finger double domain 273-296 C2H2-type zinc finger 274-296 Zinc finger, C2H2 type 274-292 C2H2-type zinc finger 288-312 Zinc-finger double domain 302-324 C2H2-type zinc finger 302-324 Zinc finger, C2H2 type 302-324 C2H2-type zinc finger 317-341 Zinc-finger double domain 329-339 C2H2-type zinc finger 330-352 C2H2-type zinc finger 330-352 Zinc finger, C2H2 type 348-368 Zinc-finger double domain 357-377 C2H2-type zinc finger 358-380 C2H2-type zinc finger 358-380 Zinc finger, C2H2 type 372-397 Zinc-finger double domain 385-408 C2H2-type zinc finger 386-408 C2H2-type zinc finger 386-408 Zinc finger, C2H2 type 403-424 Zinc-finger double domain 413-424 C2H2-type zinc finger 414-436 C2H2-type zinc finger 414-436 Zinc finger, C2H2 type 429-452 Zinc-finger double domain 442-464 Zinc finger, C2H2 type 442-464 C2H2-type zinc finger 442-461 C2H2-type zinc finger 456-481 Zinc-finger double domain 469-492 C2H2-type zinc finger 470-492 Zinc finger, C2H2 type 470-492 C2H2-type zinc finger 484-508 Zinc-finger double domain 497-508 C2H2-type zinc finger 498-520 Zinc finger, C2H2 type 498-520 C2H2-type zinc finger 513-536 Zinc-finger double domain 525-544 C2H2-type zinc finger 526-548 Zinc finger, C2H2 type 526-548 C2H2-type zinc finger 540-564 Zinc-finger double domain 554-574 C2H2-type zinc finger 554-573 C2H2-type zinc finger 554-576 Zinc finger, C2H2 type 568-592 Zinc-finger double domain 581-602 C2H2-type zinc finger 582-604 C2H2-type zinc finger 582-604 Zinc finger, C2H2 type 597-621 Zinc-finger double domain 609-628 C2H2-type zinc finger 610-632 C2H2-type zinc finger 610-632 Zinc finger, C2H2 type 624-648 Zinc-finger double domain 638-660 C2H2-type zinc finger 638-662 C2H2-type zinc finger 638-660 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MFPVLEPHQVGLIRSYNSKTMTCFQELVTFRDVAIDFSRQEWEYLDPNQRDLYRDVMLEN 60 61 YRNLVSLGGHSISKPVVVDLLERGKEPWMILREETQFTDLDLQCEIISYIEVPTYETDIS 120 121 STQLQSIYKREKLYECKKCQKKFSSGYQLILHHRFHVIERPYECKECGKNFRSGYQLTLH 180 181 QRFHTGEKPYECTECGKNFRSGYQLTVHQRFHTGEKTYECRQCGKAFIYASHIVQHERIH 240 241 TGGKPYECQECGRAFSQGGHLRIHQRVHTGEKPYKCKECGKTFSRRSNLVEHGQFHTDEK 300 301 PYICEKCGKAFRRGHQLTVHQRVHTGKKPYECKECGKGYTTASYFLLHQRIHKGGKPYEC 360 361 KECKKTFTLYRNLTRHQNIHTGEKLFECKQCGKTYTTGSKLFQHQKTHTGEKPYECKECG 420 421 KAFSLYGYLKQHQKIHTGMKHFECKECKKTFTLYRNLTRHQNIHTGKKLFECQECGKAYS 480 481 TGSNLIQHRKTHTGEKPYKCKECGKTFSLHGYLNQHQKIHTGMKPYECKVCRKTFTFYRN 540 541 LTLHQSIHTDEKPFECKECGKTFRRSSHLTAHQSIHADKKPYECKECGKAFKMYGYLTQH 600 601 QKIHTGGKPYECKECGKAFSRASNLVQHERIHTGEKPYVCKQCGKTFRYGSALKAHQRIH 660 661 RSIKV |
| Interface Residues: | 148, 173, 175, 176, 179, 183, 201, 203, 204, 206, 207, 209, 210, 213, 228, 229, 231, 232, 235, 256, 257, 258, 259, 260, 261, 262, 263, 284, 285, 286, 287, 288, 290, 291, 294, 312, 313, 314, 315, 316, 319, 341, 342, 343, 344, 346, 347, 351, 368, 369, 370, 371, 372, 374, 375, 396, 397, 399, 400, 403, 425, 426, 427, 428, 431, 452, 453, 454, 455, 456, 459, 463, 481, 483, 484, 487, 493, 507, 509, 510, 511, 512, 515, 519, 536, 537, 538, 539, 540, 543, 554, 565, 566, 567, 568, 571, 572, 592, 593, 594, 595, 596, 597, 599, 600, 620, 621, 622, 623, 624, 627, 649, 650, 651, 652, 654, 655 |
| 3D-footprint Homologues: | 5yel_A, 8ssq_A, 5kkq_D, 6ml4_A, 5yj3_D, 6e94_A, 2jpa_A, 5kl3_A, 5v3j_F, 1tf6_A, 3uk3_C, 7y3l_A, 5ei9_F, 1g2f_F, 1llm_D, 5k5l_F, 2gli_A, 2drp_D, 7w1m_H, 2lt7_A, 1tf3_A, 5k5i_A, 8ssu_A, 6u9q_A, 8gn3_A, 7ysf_A, 2kmk_A, 6blw_A, 4m9v_C, 1ubd_C, 6jnm_A, 7n5w_A, 7txc_E, 4x9j_A, 1f2i_J, 2wbs_A, 8h9h_G, 6a57_A, 8cuc_F, 7y3m_I |
| Binding Motifs: | UN0636.1 cAGcmadGGCACAMmmArgas UN0636.2 cAGcmadGGCACAMmmArg |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.