Transcription Factor
| Accessions: | A6NP11 (JASPAR 2024) |
| Names: | ZN716_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | A6NP11 |
| Length: | 495 |
| Pfam Domains: | 16-56 KRAB box 200-223 Zinc-finger double domain 213-235 C2H2-type zinc finger 213-233 C2H2-type zinc finger 213-235 Zinc finger, C2H2 type 228-251 Zinc-finger double domain 241-263 Zinc finger, C2H2 type 241-263 C2H2-type zinc finger 241-261 C2H2-type zinc finger 255-279 Zinc-finger double domain 286-307 Zinc-finger double domain 295-316 C2H2-type zinc finger 296-318 Zinc finger, C2H2 type 296-318 C2H2-type zinc finger 311-334 Zinc-finger double domain 323-344 C2H2-type zinc finger 324-346 Zinc finger, C2H2 type 324-346 C2H2-type zinc finger 339-362 Zinc-finger double domain 351-372 C2H2-type zinc finger 352-374 Zinc finger, C2H2 type 352-374 C2H2-type zinc finger 367-390 Zinc-finger double domain 379-402 C2H2-type zinc finger 380-402 C2H2-type zinc finger 380-402 Zinc finger, C2H2 type 395-418 Zinc-finger double domain 407-427 C2H2-type zinc finger 408-430 C2H2-type zinc finger 408-430 Zinc finger, C2H2 type 423-446 Zinc-finger double domain 435-456 C2H2-type zinc finger 436-458 C2H2-type zinc finger 436-458 Zinc finger, C2H2 type 451-474 Zinc-finger double domain 463-481 C2H2-type zinc finger 464-486 C2H2-type zinc finger 464-486 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MAKRPGPPGSREMGLLTFRDIAIEFSLAEWQCLDHAQQNLYRDVMLENYRNLVSLGIAVS 60 61 KPDLITCLEQNKEPQNIKRNEMVAKHPVTCSHFTQDLQSEQGIKDSLQKVILRRYGKCGQ 120 121 EDLQVKKCCKSVGECEVHKGGYNYVNQCLSATQNKTFQTHKCVKVFGKFSNSNRHKTRHT 180 181 GKKHFKCKNDGKSFCMLSRLNQHQIIHTREKSYKCEECGKSFNCSSTLTRHKRIHTGEKP 240 241 YRCEECGKAFSWSASLTKHKRIHTGEKPYTCEERGKVFSRSTLTNYKRIHTGEKPYTCEE 300 301 CGKAFSRSSTLTNHKRIHTGERPYKCEECGKAFSLSSTLKKHKIVHTGEKLYTCEECGKA 360 361 FTFSSTLNTHKRIHTGEKPYTCEECGKAFSLPSTFTYHKRTHTGEKPYKCEECGKAFNCS 420 421 STLKKHKIIHTGEKLYKCKECGKAFTFSSTLNTHKRIHTGEKPYKCEECDQTFKWHSSLA 480 481 NHKNMHTGEKPYKYE |
| Interface Residues: | 56, 57, 60, 61, 223, 224, 226, 227, 230, 234, 251, 252, 254, 255, 258, 279, 280, 281, 282, 284, 285, 286, 288, 289, 296, 306, 307, 308, 309, 310, 312, 313, 314, 334, 335, 336, 337, 338, 339, 340, 341, 342, 344, 362, 363, 364, 365, 366, 367, 368, 369, 371, 390, 391, 392, 393, 394, 396, 397, 399, 400, 403, 419, 420, 421, 422, 423, 424, 425, 431, 445, 446, 447, 448, 449, 450, 453, 457, 474, 475, 476, 477, 478, 480, 481 |
| 3D-footprint Homologues: | 4nhj_A, 6jnm_A, 1tf6_A, 8ssq_A, 7w1m_H, 6a57_A, 8ssu_A, 6blw_A, 4x9j_A, 5v3j_F, 2kmk_A, 8cuc_F, 7y3l_A, 1tf3_A, 2wbs_A, 6u9q_A, 5ei9_F, 1llm_D, 1f2i_J, 4m9v_C, 8h9h_G, 7y3m_I, 2lt7_A, 5yel_A, 1ubd_C, 5kkq_D, 8gn3_A, 5yj3_D, 2drp_D, 6ml4_A, 2gli_A, 7ysf_A, 7n5w_A, 1g2f_F, 7txc_E, 5k5i_A, 6e94_A, 2jpa_A, 5kl3_A, 3uk3_C, 5k5l_F |
| Binding Motifs: | UN0652.1 wrrCAGGAAATAkwr UN0652.2 CAGGAAATA |
| Binding Sites: | UN0652.1.1 UN0652.1.10 / UN0652.1.13 UN0652.1.11 / UN0652.1.15 UN0652.1.12 / UN0652.1.16 UN0652.1.13 / UN0652.1.17 UN0652.1.14 / UN0652.1.18 UN0652.1.15 / UN0652.1.19 UN0652.1.16 / UN0652.1.20 UN0652.1.17 UN0652.1.18 UN0652.1.19 UN0652.1.2 UN0652.1.20 UN0652.1.3 UN0652.1.4 / UN0652.1.5 UN0652.1.5 / UN0652.1.6 UN0652.1.6 / UN0652.1.7 UN0652.1.7 / UN0652.1.9 UN0652.1.10 / UN0652.1.8 UN0652.1.12 / UN0652.1.9 UN0652.1.11 UN0652.1.14 UN0652.1.3 UN0652.1.4 UN0652.1.8 UN0652.2.1 UN0652.2.10 UN0652.2.11 UN0652.2.12 UN0652.2.13 / UN0652.2.6 UN0652.2.14 / UN0652.2.16 / UN0652.2.5 / UN0652.2.9 UN0652.2.15 UN0652.2.17 UN0652.2.18 / UN0652.2.8 UN0652.2.19 UN0652.2.2 UN0652.2.20 UN0652.2.3 UN0652.2.4 UN0652.2.7 |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.