Transcription Factor

						

			
Accessions: 5iyd_P (3D-footprint 20241219)

			
Names: TATA sequence-binding protein, TATA-binding factor, TATA-box factor, TATA-box-binding protein, TBP_HUMAN, Transcription initiation factor TFIID TBP subunit
Organisms: Homo sapiens
Libraries: 3D-footprint 20241219 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P20226
Length: 185
Pfam Domains:     11-93 Transcription factor TFIID (or TATA-binding protein, TBP)
   99-183 Transcription factor TFIID (or TATA-binding protein, TBP)
Sequence: 
(in bold interface residues)		   1 TPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTAL   60
  61 IFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEG  120
 121 LVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPIL  180
 181 KGFRK
Interface Residues: 15, 17, 45, 46, 60, 62, 68, 70, 105, 107, 136, 137, 151, 153, 159, 161
3D-footprint Homologues: 7z7n_D, 1ytb_A
Binding Motifs: 5iyd_P TTTTATA
Binding Sites: 5iyd_X
5iyd_Y
			
Publications: He Y, Yan C, Fang J, Inouye C, Tjian R, Ivanov I, Nogales E. Near-atomic resolution visualization of human transcription promoter opening. Nature 533:359-65 (2016). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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