Transcription Factor

Accessions: T095968_1.02 (CISBP 1.02)
Names: six3, T095968_1.02;
Organisms: Oryzias latipes
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:Homeodomain
Length: 280
Pfam Domains: 183-233 Homeobox domain
197-231 Homeobox KN domain
Sequence:
(in bold interface residues)
1 ACLPTRAQMVFRAPLDFISASRLLLPHFADAPPVLSRSRSPEHPPAGFLSFALPGLCFSA 60
61 TQIASVCETLEETGDIERLARFLWSLPVNTDGRDSISEHESVQRARAVVAFHTGCYRELY 120
121 RILETHRFTRASHSKLQAMWLEAHYREAEKLRGRPLGPVDKYRVRKKFPLPRTIWDGEQK 180
181 THCFKERTRGLLREWYLQDPYPNPGKKRELAHATGLTPTQVGNWFKNRRQRDRAAAAKNR 240
241 LQHHRICPDSACTLSGGDSSERADGDTFLSVTDSDSDLDV
Interface Residues: 172, 178, 180, 181, 182, 183, 219, 220, 222, 223, 226, 227, 230, 231, 234
3D-footprint Homologues: 6m3d_C, 4xrs_G, 5zfz_A, 8ejp_B, 1mnm_C, 2r5y_A, 1puf_B, 1k61_B, 1le8_B, 5jlw_D, 2ld5_A, 8osb_E, 4j19_B, 1le8_A, 7q3o_C, 2xsd_C, 1ig7_A, 7xrc_C, 4xrm_B, 3a01_E, 1jgg_B, 4cyc_A, 2lkx_A, 8bx1_A, 1du0_A, 6es3_K, 3cmy_A, 1zq3_P, 8pmf_A, 7psx_B, 1nk2_P, 1fjl_B, 6fqp_B, 5flv_I, 3lnq_A, 2hdd_A, 9b8u_A, 5zjt_E, 4qtr_D, 1puf_A, 8g87_X, 6fqq_E, 5hod_A, 3rkq_B, 1b72_A, 6a8r_A
Binding Motifs: M1074_1.02 mtkAtmyccc
Related annotations: PaperBLAST

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