Transcription Factor
| Accessions: | E9Q3T6 (JASPAR 2024) |
| Names: | EC 2.1.1.-, PR domain zinc finger protein 14, PR domain-containing protein 14, PRD14_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | E9Q3T6 |
| Length: | 561 |
| Pfam Domains: | 256-356 SET domain 390-410 C2H2-type zinc finger 390-400 C2H2-type zinc finger 422-434 C2H2-type zinc finger 422-445 C2H2-type zinc finger 437-461 Zinc-finger double domain 451-473 C2H2-type zinc finger 451-473 Zinc finger, C2H2 type 451-473 C2H2-type zinc finger 465-489 Zinc-finger double domain 479-502 C2H2-type zinc finger 479-501 Zinc finger, C2H2 type 479-501 C2H2-type zinc finger 494-517 Zinc-finger double domain 507-519 C2H2-type zinc finger 537-558 Zinc finger, C2H2 type 537-558 C2H2-type zinc finger 538-558 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MALPPSGETQSQDKANYLPQSNPHHLTTYYAHAPGYSHFRNLATTEEEFQPWKLAAAVLE 60 61 SQAMAPLDAFRMTAPLLNPGLAVQSEPLYNLPWYKLSPWNRIPQFTPEVPRFLDSTEHRS 120 121 SGSSNQNLVLGGGGGQISGQRWEAENLLLPSPVIASLLPDGIKSSQSISVPQTLNQEGKL 180 181 PFCGFNFTEEELSFVLYGAIASPEHPTDLQHAISGILVPTESSGSNHLHKTLDKDSLQLP 240 241 EGLCLMQTSFGDVPHFGVFCSDFIAKGVRFGPFRGRVVNASEVKAHRDNSRMWEIFEDGH 300 301 LSHFIDGKGSGNWMSYVNCARFPKEQNLLAVQHQGQIFYESCRDIQRNQELLVWYGNGYE 360 361 KFLGVPMNLRVTEQGGQQLSESSEESAEGYRCERCGKVFTYKYYRDKHLKYTPCVDKGDR 420 421 KFPCSLCQRSFEKRDRLRIHILHVHERHRPYLCSTCGKSFSQSSSLNKHMRVHSGDRPYQ 480 481 CVYCTKKFTASSILRTHIRQHSGEKPFKCKHCGKAFASHAAHDSHVRRSHKDNGRSSCDI 540 541 CGKGFLDQEAFYAHMRLHKTC |
| Interface Residues: | 400, 401, 402, 403, 404, 406, 407, 411, 422, 433, 434, 435, 436, 438, 439, 441, 442, 443, 446, 461, 462, 463, 464, 465, 467, 468, 469, 489, 490, 491, 492, 493, 494, 495, 496, 497, 500, 517, 518, 519, 520, 521, 522, 523, 524, 525, 526, 528, 529, 546, 547, 548, 549, 550, 552, 553, 556 |
| 3D-footprint Homologues: | 7w1m_H, 6wmi_A, 2drp_D, 5v3j_F, 5kkq_D, 2i13_A, 2kmk_A, 8ssq_A, 5und_A, 8ssu_A, 5yel_A, 6e94_A, 7ysf_A, 2jpa_A, 1ubd_C, 6jnm_A, 3uk3_C, 8cuc_F, 1tf3_A, 7y3l_A, 7n5w_A, 5kl3_A, 5ei9_F, 1mey_C, 1f2i_J, 5k5i_A, 6ml4_A, 2gli_A, 8gn3_A, 1g2f_F, 6blw_A, 1tf6_A, 6u9q_A, 4x9j_A, 7txc_E, 7eyi_G, 4m9v_C, 8h9h_G, 2lt7_A, 7y3m_I, 6a57_A, 2wbs_A, 5yj3_D, 1llm_D |
| Binding Motifs: | MA1998.1 hrGGTCTCTAac MA1998.2 GGTCTCTA |
| Binding Sites: | MA1998.2.6 MA1998.1.1 MA1998.1.10 / MA1998.1.16 MA1998.1.11 / MA1998.1.17 MA1998.1.12 / MA1998.1.18 MA1998.1.13 / MA1998.1.19 MA1998.1.14 / MA1998.1.20 MA1998.1.15 MA1998.1.16 MA1998.1.17 MA1998.1.18 MA1998.1.19 MA1998.1.2 MA1998.1.20 MA1998.1.3 / MA1998.1.5 MA1998.1.4 / MA1998.1.6 MA1998.1.5 / MA1998.1.7 MA1998.1.6 / MA1998.1.8 MA1998.1.7 / MA1998.1.9 MA1998.1.13 / MA1998.1.8 MA1998.1.15 / MA1998.1.9 MA1998.1.10 MA1998.1.11 MA1998.1.12 MA1998.1.14 MA1998.1.3 MA1998.1.4 MA1998.2.1 / MA1998.2.11 / MA1998.2.13 / MA1998.2.4 MA1998.2.10 / MA1998.2.2 MA1998.2.12 MA1998.2.14 MA1998.2.15 / MA1998.2.17 MA1998.2.16 MA1998.2.18 / MA1998.2.5 MA1998.2.19 / MA1998.2.8 MA1998.2.20 MA1998.2.3 MA1998.2.7 MA1998.2.9 |
| Publications: | Chia NY, Chan YS, Feng B, Lu X, Orlov YL, Moreau D, Kumar P, Yang L, Jiang J, Lau MS, Huss M, Soh BS, Kraus P, Li P, Lufkin T, Lim B, Clarke ND, Bard F, Ng HH. A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity. Nature 468:316-20 (2010). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.