Transcription Factor
| Accessions: | VSX1_full (HumanTF 1.0) |
| Names: | Homeodomain protein RINX, Retinal inner nuclear layer homeobox protein, Transcription factor VSX1, Visual system homeobox 1, VSX1, VSX1_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | HumanTF 1.0 1 1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
| Uniprot: | Q9NZR4 |
| Notes: | Ensembl ID: ENSG00000100987; Full protein sequence; TF family: homeodomain; Clone source: hORFeome |
| Length: | 366 |
| Pfam Domains: | 165-221 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MTGRDSLSDGRTSSRALVPGGSPRGSRPRGFAITDLLGLEAELPAPAGPGQGSGCEGPAV 60 61 APCPGPGLDGSSLARGALPLGLGLLCGFGTQPPAAARAPCLLLADVPFLPPRGPEPAAPL 120 121 APSRPPPALGRQKRSDSVSTSDEDSQSEDRNDLKASPTLGKRKKRRHRTVFTAHQLEELE 180 181 KAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREKRWGGSSVMAEYGLYGA 240 241 MVRHCIPLPDSVLNSAEGGLLGSCAPWLLGMHKKSMGMIRKPGSEDKLAGLWGSDHFKEG 300 301 SSQSESGSQRGSDKVSPENGLEDVAIDLSSSARQETKKVHPGAGAQGGSNSTALEGPQPG 360 361 KVGAT* |
| Interface Residues: | 135, 136, 137, 140, 141, 147, 151, 164, 165, 166, 167, 168, 206, 207, 209, 210, 213, 214, 216, 217, 218, 221, 222 |
| 3D-footprint Homologues: | 1au7_A, 4j19_B, 8ejp_B, 6a8r_A, 1fjl_B, 3cmy_A, 8pmf_A, 1ig7_A, 5zfz_A, 1puf_A, 3d1n_M, 1puf_B, 3lnq_A, 1nk2_P, 1zq3_P, 2lkx_A, 6m3d_C, 1jgg_B, 2ld5_A, 7q3o_C, 6es3_K, 7psx_B, 5hod_A, 3a01_E, 8osb_E, 5jlw_D, 3rkq_B, 8eml_B, 1b72_A, 4xrs_G, 2hdd_A, 4cyc_A, 2r5y_A, 5flv_I, 2hos_A, 9b8u_A, 5zjt_E, 8ik5_C, 1e3o_C, 7xrc_C, 2xsd_C, 4qtr_D, 1o4x_A, 8g87_X, 1du0_A, 8bx1_A |
| Binding Motifs: | VSX1_full rgcyAATTrrc |
| Publications: | Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
| Related annotations: | PaperBLAST |
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