Transcription Factor
| Accessions: | 2zhg_A (3D-footprint 20231221) |
| Names: | Redox-sensitive transcriptional activator soxR, SOXR_ECOLI |
| Organisms: | Escherichia coli, strain K12 |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | P0ACS2 |
| Length: | 121 |
| Pfam Domains: | 4-67 MerR HTH family regulatory protein 4-40 MerR family regulatory protein 46-105 MerR, DNA binding |
| Sequence: (in bold interface residues) | 1 ALLTPGEVAKRSGVAVSALHFYESKGLITSIRNSGNQRRYKRDVLRYVAIIKIAQRIGIP 60 61 LATIGEAFGVTLSAKEWKQLSSQWREELDRRIHTLVALRDELDGCIGCGCLSRSDCPLRN 120 121 P |
| Interface Residues: | 15, 16, 17, 20, 21, 24, 37, 38, 39 |
| 3D-footprint Homologues: | 6amk_B, 6ama_L, 4aik_A, 1r8e_A, 7ckq_G, 4r4e_B, 6jgx_B, 2vz4_A, 7tec_A, 5d8c_A, 6ldi_G, 2zhg_A, 1r8d_B, 6xh7_H |
| Binding Motifs: | 2zhg_A aCtt |
| Binding Sites: | 2zhg_B |
| Publications: | Watanabe S, Kita A, Kobayashi K, Miki K. Crystal structure of the [2Fe-2S] oxidative-stress sensor SoxR bound to DNA. Proceedings of the National Academy of Sciences of the United States of America 105:4121-6 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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