Transcription Factor
| Accessions: | Q0VG99 (JASPAR 2024) |
| Names: | bHLHc6, Class C basic helix-loop-helix protein 6, Mesoderm posterior protein 2, MESP2_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q0VG99 |
| Length: | 397 |
| Pfam Domains: | 82-135 Helix-loop-helix DNA-binding domain |
| Sequence: (in bold interface residues) | 1 MAQSPPPQSLLGHDHWIFAQGWGWAGHWDSTSPASSSDSSGSCPCDGARGLPQPQPPSCS 60 61 SRAAEAAATTPRRARTGPAGGQRQSASEREKLRMRTLARALHELRRFLPPSLAPAGQSLT 120 121 KIETLRLAIRYIGHLSAVLGLSEESLQCRRRQRGDAGSPWGCPLCPDRGPAEAQTQAEGQ 180 181 GQGQGQGQGQGQGQGQGQGQGQGQGRRPGLVSAVLAEASWGSPSACPGAQAAPERLGRGV 240 241 HDTDPWATPPYCPKIQSPPYSSQGTTSDASLWTPPQGCPWTQSSPEPRNPPVPWTAAPAT 300 301 LELAAVYQGLSVSPEPCLSLGAPSLLPHPSCQRLQPQTPGRCWSHSAEVVPNSEDQGPGA 360 361 AFQLSEASPPQSSGLRFSGCPELWQEDLEGARLGIFY |
| Interface Residues: | 83, 86, 87, 89, 90, 91, 93, 94 |
| 3D-footprint Homologues: | 8osb_B, 1a0a_B, 7z5k_B, 2ypa_A, 6od3_F, 2ypa_B, 2ql2_A, 2ql2_D |
| Binding Motifs: | UN0131.1 cAmCATATGkyg |
| Related annotations: | PaperBLAST |
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