Transcription Factor

Accessions: Q7TPZ5 (JASPAR 2024)
Names: Q7TPZ5_MOUSE
Organisms: Mus musculus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q7TPZ5
Length: 291
Pfam Domains: 95-151 Homeobox domain
Sequence:
(in bold interface residues)
1 MAEGPSLHPKLQVASNIPIEIRSQIPQEPARNLAFQMSQSPLVTPGSTMQSSLSVPERNL 60
61 LQQESEGSSRQSGSMPLSDKYVNKQTGPMASRKFRKERTVYTKEQQRLLQKHFDECQYPN 120
121 EKKIMELAVSVGVTKMEIKIWFKNNRAKYRRMNLQNIKQALPESNGISKAVSESTHFPGS 180
181 IPVVASDNGESMCSGTFGEDSMPKFNCSQESFLYCFQACDGDMCCPQEYLLDGHAPVTAW 240
241 NSGQSAAVEYQTDIAVAEAPVRLAYAAQAPEDAHNSGPSADELWQRILEDF
Interface Residues: 90, 93, 95, 96, 97, 98, 136, 137, 139, 140, 143, 144, 147, 148, 151, 152
3D-footprint Homologues: 1mnm_C, 1ig7_A, 5zfz_A, 2h1k_B, 1puf_A, 3cmy_A, 6a8r_A, 3d1n_M, 1fjl_B, 1zq3_P, 3lnq_A, 2lkx_A, 1jgg_B, 1nk2_P, 6es3_K, 2ld5_A, 7q3o_C, 4cyc_A, 1b72_A, 4xrs_G, 3l1p_A, 4j19_B, 3a01_E, 6m3d_C, 5flv_I, 5zjt_E, 2hdd_A, 7psx_B, 5hod_A, 3rkq_B, 2r5y_A, 1puf_B, 1au7_A, 2hos_A, 5jlw_D, 2xsd_C, 1le8_A, 7xrc_C, 1e3o_C, 1o4x_A, 1le8_B, 1du0_A, 8g87_X, 4qtr_D, 1k61_B, 4xrm_B
Binding Motifs: PH0124.1 wdrrGGGATTAAwTywm
PH0125.1 kwyAwTTAATCCctyyt
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.