Transcription Factor
Accessions: | 5c8e_C (3D-footprint 20231221) |
Names: | Light-dependent transcriptional regulator CarH, Q746J7_THET2 |
Organisms: | strain HB27 / ATCC BAA-163 / DSM 7039, Thermus thermophilus |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Uniprot: | Q746J7 |
Length: | 279 |
Pfam Domains: | 8-76 MerR HTH family regulatory protein 9-46 MerR family regulatory protein 85-157 B12 binding domain |
Sequence: (in bold interface residues) | 1 HMTSSGVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPGGHRLYSAEDVEALKTIKRW 60 61 LEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHL 120 121 LLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEI 180 181 GAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKD 240 241 LAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPR |
Interface Residues: | 22, 25, 26, 29, 30, 43 |
3D-footprint Homologues: | 5d8c_A, 6xh7_H, 4r24_B, 5i44_I, 7tea_B, 4r4e_B, 6jgx_B, 7tec_A, 5c8e_C, 6ldi_G, 1r8d_B |
Binding Motifs: | 5c8e_BC TACAnnnnnnTGACA 5c8e_C TgTCa |
Binding Sites: | 5c8e_I 5c8e_J |
Publications: | Jost M, Fernández-Zapata J, Polanco MC, Ortiz-Guerrero JM, Chen PY, Kang G, Padmanabhan S, ElÃas-Arnanz M, Drennan CL. Structural basis for gene regulation by a B12-dependent photoreceptor. Nature 526:536-41 (2015). [Pubmed] |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.