Transcription Factor

						

			
Accessions: 5c8e_C (3D-footprint 20231221)

			
Names: Light-dependent transcriptional regulator CarH, Q746J7_THET2
Organisms: strain HB27 / ATCC BAA-163 / DSM 7039, Thermus thermophilus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q746J7
Length: 279
Pfam Domains:      8-76 MerR HTH family regulatory protein
     9-46 MerR family regulatory protein
   85-157 B12 binding domain
Sequence: 
(in bold interface residues)		   1 HMTSSGVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPGGHRLYSAEDVEALKTIKRW   60
  61 LEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHL  120
 121 LLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEI  180
 181 GAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKD  240
 241 LAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPR
Interface Residues: 22, 25, 26, 29, 30, 43
3D-footprint Homologues: 6ldi_G, 1r8d_B, 5d8c_A, 6xh7_H, 4r24_B, 5i44_I, 7tea_B, 4r4e_B, 6jgx_B, 7tec_A, 5c8e_C
Binding Motifs: 5c8e_BC TACAnnnnnnTGACA
5c8e_C TgTCa
Binding Sites: 5c8e_I
5c8e_J
			
Publications: Jost M, Fernández-Zapata J, Polanco MC, Ortiz-Guerrero JM, Chen PY, Kang G, Padmanabhan S, Elías-Arnanz M, Drennan CL. Structural basis for gene regulation by a B12-dependent photoreceptor. Nature 526:536-41 (2015). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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