Transcription Factor

Accessions: 6mg2_A (3D-footprint 20231221)
Names: C/EBP beta, CCAAT/enhancer-binding protein beta, CEBPB_HUMAN, LAP, LIP, Liver activator protein, Liver-enriched inhibitory protein, Nuclear factor NF-IL6, TCF-5, Transcription factor 5
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P17676
Length: 65
Pfam Domains: 3-56 Basic region leucine zipper
4-62 bZIP transcription factor
Sequence:
(in bold interface residues)
1 MKHSDEYKIRRERNNIAVRKSRDKAKMRNLETQHKVLELTAENERLQKKVEQLSRELSTL 60
61 RNLFK
Interface Residues: 10, 11, 14, 15, 17, 18, 21, 22
3D-footprint Homologues: 2wt7_A, 1nwq_C, 6mg1_B, 2c9l_Z, 2dgc_A
Binding Motifs: 6mg2_AB ATTGCGnAAT
Publications: Yang J, Horton JR, Wang D, Ren R, Li J, Sun D, Huang Y, Zhang X, Blumenthal RM, Cheng X. Structural basis for effects of CpA modifications on C/EBPβ binding of DNA. Nucleic Acids Res : (2018). [Pubmed]
Related annotations: PaperBLAST

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