Transcription Factor

Accessions: 6akp_C (3D-footprint 20231221)
Names: Forkhead box protein C2, Forkhead-related protein FKHL14, FOXC2_HUMAN, Mesenchyme fork head protein 1, MFH-1 protein, Transcription factor FKH-14
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q99958
Length: 94
Pfam Domains: 3-93 Fork head domain
Sequence:
(in bold interface residues)
1 GPKPPYSYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYRENKQGWQNSIRHNLSLNEC 60
61 FVKVPRDKGSYWTLDPDSYNMFENGSFLRRRRRF
Interface Residues: 43, 46, 48, 49, 50, 52, 53, 54, 56, 57, 66, 68, 90, 93
3D-footprint Homologues: 3l2c_A, 7vox_H, 2hdc_A, 7yz7_A, 6el8_A, 7tdx_A, 7yzb_A, 6nce_A, 2uzk_A, 7vou_C, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 6ako_C, 2c6y_A, 7yzg_A, 7tdw_A, 3g73_A, 3qrf_G
Binding Motifs: 6akp_C anaCA
Binding Sites: 6akp_A / 6akp_B
Publications: Chen X, Wei H, Li J, Liang X, Dai S, Jiang L, Guo M, Qu L, Chen Z, Chen L, Chen Y. Structural basis for DNA recognition by FOXC2. Nucleic Acids Res 47:3752-3764 (2019). [Pubmed]
Related annotations: PaperBLAST

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