Transcription Factor

Accessions: 1xpx_A (3D-footprint 20231221)
Names: PROS_DROME, Protein prospero
Organisms: Drosophila melanogaster
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P29617
Length: 144
Pfam Domains: 1-144 Homeobox prospero-like protein (PROX1)
Sequence:
(in bold interface residues)
1 SSTLTPMHLRKAKLMFFWVRYPSSAVLKMYFPDIKFNKNNTAQLVKWFSNFREFYYIQME 60
61 KYARQAVTESELYRVLNLHYNRNNHIEVPQNFRFVVESTLREFFRAIQGGKDTEQSWKKS 120
121 IYKIISRMDDPVPEYFKSPNFLEQ
Interface Residues: 46, 49, 50, 53, 54
3D-footprint Homologues: 1xpx_A, 1zq3_P
Binding Motifs: 1xpx_A cCTg
Binding Sites: 1xpx_C
1xpx_D
Publications: Yousef M.S, Matthews B.W. Structural basis of Prospero-DNA interaction: implications for transcription regulation in developing cells. Structure (London, England : 1993) 13:601-7 (2005). [Pubmed]
Related annotations: PaperBLAST

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