Transcription Factor
Accessions: | 5hod_D (3D-footprint 20231221) |
Names: | LHX4_HUMAN, LIM homeobox protein 4, LIM/homeobox protein Lhx4 |
Organisms: | Homo sapiens |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Uniprot: | Q969G2 |
Length: | 58 |
Pfam Domains: | 1-56 Homeobox domain 13-52 Homeobox KN domain |
Sequence: (in bold interface residues) | 1 RPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLK |
Interface Residues: | 1, 2, 3, 41, 42, 44, 45, 48, 49, 52, 53, 56 |
3D-footprint Homologues: | 3lnq_A, 2lkx_A, 1zq3_P, 1jgg_B, 6m3d_C, 2ld5_A, 3a01_E, 2h1k_B, 6ryd_F, 1au7_A, 5hod_A, 1fjl_B, 6a8r_A, 3cmy_A, 2hdd_A, 1b72_A, 5jlw_D, 3rkq_B, 2r5y_A, 1ig7_A, 4xrs_G, 3d1n_M, 2hos_A, 5zfz_A, 4cyc_A, 2d5v_B, 8pop_A, 5flv_I, 3l1p_A, 7q3o_C, 1e3o_C, 1le8_A, 7xrc_C, 2xsd_C, 1puf_A, 5zjt_E, 4qtr_D, 1puf_B, 4xrm_B, 1nk2_P, 6wig_A, 8g87_X, 6es3_K, 1o4x_A, 7psx_B, 1du0_A |
Binding Motifs: | 5hod_AD CAATnAGnnGTAATna |
Binding Sites: | 5hod_B 5hod_C |
Publications: | Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.