Transcription Factor

						

			
Accessions: 3mzh_A (3D-footprint 20231221), 3mzh_B (3D-footprint 20231221)

			
Names: cAMP receptor protein, cAMP regulatory protein, CRP-like cAMP-activated global transcriptional regulator, CRPL_MYCTU, PROBABLY CRP/FNR-FAMILY
Organisms: Mycobacterium tuberculosis, strain ATCC 25618 / H37Rv
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P9WMH3
Length: 225
Pfam Domains:    30-119 Cyclic nucleotide-binding domain
  149-222 Crp-like helix-turn-helix domain
  175-204 Bacterial regulatory proteins, crp family
Sequence: 
(in bold interface residues)		   1 HMDEILARAGIFQGVEPSAIAALTKQLQPVDFPRGHTVFAEGEPGDRLYIIISGKVKIGR   60
  61 RAPDGRENLLTIMGPSDMFGELSIFDPGPRTSSATTITEVRAVSMDRDALRSWIADRPEI  120
 121 SEQLLRVLARRLRRTNNNLADLIFTDVPGRVAKQLLQLAQRFGTQEGGALRVTHDLTQEE  180
 181 IAQLVGASRETVNKALADFAHRGWIRLEGKSVLISDSERLARRAR
Interface Residues: 35, 141, 145, 178, 179, 188, 189, 190, 191, 193, 194
3D-footprint Homologues: 3iyd_H, 4y60_C, 4p9u_F, 1h9t_B, 3mzh_A, 5i2d_R, 4i2o_B, 7pza_B, 3e6c_C
Binding Motifs: 3mzh_A TGTGA
3mzh_AB TGTGAnnnnnGTCACG
Binding Sites: 3mzh_C
3mzh_D
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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