Transcription Factor

						

			
Accessions: 4ki2_B (3D-footprint 20231221)

			
Names: RNA polymerase sigma factor, SIGA_THEAQ
Organisms: Thermus aquaticus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q9EZJ8
Length: 234
Pfam Domains:      1-36 Sigma-70 factor, region 1.2
  110-180 Sigma-70 region 2 
  189-233 Sigma-70 region 3
Sequence: 
(in bold interface residues)		   1 SDPVRQYLHEIGQVPLLTLEEEIDLARKVEEGMEAIKKLSEATGLDQELIREVVRAKILG   60
  61 TARIQKIPGLKEKPDPKTVEEVDGKLKSLPKELKRYLHIAREGEAARQHLIEANLRLVVS  120
 121 IAKKYTGRGLSFLDLIQEGNQGLIRAVEKFEYKRRFKFSTYATWWIRQAINRAIADQART  180
 181 IRIPVHMVETINKLSRTARQLQQELGREPSYEEIAEAMGPGWDAKRVEETLKIA
Interface Residues: 101, 104
3D-footprint Homologues: 4awl_A
Binding Motifs: 4ki2_B TAnAAT
			
Publications: Feklistov A, Darst SA. Crystallographic analysis of an RNA polymerase σ-subunit fragment complexed with -10 promoter element ssDNA: quadruplex formation as a possible tool for engineering crystal contacts in protein-ssDNA complexes. Acta Crystallogr Sect F Struct Biol Cryst Commun : (2013). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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