Transcription Factor
| Accessions: | XBP1 (HT-SELEX2 May2017) |
| Names: | ENSG00000100219, XBP1 |
| Organisms: | Homo sapiens |
| Libraries: | HT-SELEX2 May2017 1 1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] |
| Notes: | TF family: bZIP experiment: HT-SELEX Hamming distance: 1 cycle: 4, TF family: bZIP experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 4 |
| Length: | 376 |
| Pfam Domains: | 69-120 Basic region leucine zipper 70-126 bZIP transcription factor |
| Sequence: (in bold interface residues) | 1 MVVVAAAPNPADGTPKVLLLSGQPASAAGAPAGQALPLMVPAQRGASPEAASGGLPQARK 60 61 RQRLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLLR 120 121 EKTHGLVVENQELRQRLGMDALVAEEEAEAKGNEVRPVAGSAESAAGAGPVVTPPEHLPM 180 181 DSGGIDSSDSESDILLGILDNLDPVMFFKCPSPEPASLEELPEVYPEGPSSLPASLSLSV 240 241 GTSSAKLEAINELIRFDHIYTKPLVLEIPSETESQANVVVKIEEAPLSPSENDHPEFIVS 300 301 VKEEPVEDDLVPELGISNLLSSSHCPKPSSCLLDAYSDCGYGGSLSPFSDMSSLLGVNHS 360 361 WEDTFANELFPQLISV |
| Interface Residues: | 76, 77, 79, 80, 81, 83, 84, 87, 88, 91 |
| 3D-footprint Homologues: | 2wt7_A, 7x5e_E, 7x5e_F, 1gd2_G, 1skn_P, 8k86_A, 6mg1_B, 1dh3_C, 5t01_B, 5vpe_D |
| Binding Motifs: | XBP1_3 bgmCACGTCAys XBP1_4 srTgACGTcAys XBP1_methyl_1 ygmCACrTCAyc XBP1_methyl_2 srTGAyGTcAys |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.