Transcription Factor
Accessions: | 4hca_A (3D-footprint 20231221) |
Names: | GATA-binding factor 3, GATA3_HUMAN, Trans-acting T-cell-specific transcription factor GATA-3 |
Organisms: | Homo sapiens |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Uniprot: | P23771 |
Length: | 99 |
Pfam Domains: | 5-38 GATA zinc finger 48-80 GATA zinc finger |
Sequence: (in bold interface residues) | 1 MGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPTSCANCQTTTTTLWR 60 61 RNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKM |
Interface Residues: | 14, 15, 17, 27, 31, 57, 58, 60, 70, 74, 75, 78, 95, 97, 98 |
3D-footprint Homologues: | 4hc9_A, 3vd6_C, 3dfx_B, 1gat_A, 4gat_A |
Binding Motifs: | 4hca_A tTCTGATAa |
Binding Sites: | 4hca_X 4hca_Y |
Publications: | Chen Y, Bates D.L, Dey R, Chen P.H, Machado A.C, Laird-Offringa I.A, Rohs R, Chen L. DNA binding by GATA transcription factor suggests mechanisms of DNA looping and long-range gene regulation. Cell reports 2:1197-206 (2012). [Pubmed] |
Related annotations: | PaperBLAST |
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