Transcription Factor
| Accessions: | O75437 (JASPAR 2024) |
| Names: | BMZF-5, Bone marrow zinc finger 5, HD-ZNF1, Hematopoietic cell-derived zinc finger protein 1, Zinc finger protein 254, Zinc finger protein 539, Zinc finger protein 91-like, ZN254_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | O75437 |
| Length: | 659 |
| Pfam Domains: | 13-53 KRAB box 210-229 C2H2-type zinc finger 210-230 Zinc finger, C2H2 type 210-229 C2H2-type zinc finger 253-276 Zinc-finger double domain 265-285 C2H2-type zinc finger 266-288 Zinc finger, C2H2 type 266-288 C2H2-type zinc finger 280-303 Zinc-finger double domain 293-314 C2H2-type zinc finger 294-316 Zinc finger, C2H2 type 309-331 Zinc-finger double domain 321-344 C2H2-type zinc finger 322-344 C2H2-type zinc finger 322-344 Zinc finger, C2H2 type 337-360 Zinc-finger double domain 349-369 C2H2-type zinc finger 350-372 C2H2-type zinc finger 350-372 Zinc finger, C2H2 type 365-389 Zinc-finger double domain 378-400 Zinc finger, C2H2 type 378-397 C2H2-type zinc finger 393-416 Zinc-finger double domain 405-425 C2H2-type zinc finger 406-428 C2H2-type zinc finger 406-428 Zinc finger, C2H2 type 420-443 Zinc-finger double domain 433-454 C2H2-type zinc finger 434-456 Zinc finger, C2H2 type 449-471 Zinc-finger double domain 461-484 C2H2-type zinc finger 462-484 Zinc finger, C2H2 type 462-484 C2H2-type zinc finger 477-500 Zinc-finger double domain 489-509 C2H2-type zinc finger 490-512 Zinc finger, C2H2 type 490-512 C2H2-type zinc finger 505-528 Zinc-finger double domain 517-537 C2H2-type zinc finger 518-540 Zinc finger, C2H2 type 518-540 C2H2-type zinc finger 533-557 Zinc-finger double domain 545-566 C2H2-type zinc finger 546-568 Zinc finger, C2H2 type 546-568 C2H2-type zinc finger 561-584 Zinc-finger double domain 573-593 C2H2-type zinc finger 574-596 Zinc finger, C2H2 type 574-593 C2H2-type zinc finger 589-611 Zinc-finger double domain 601-621 C2H2-type zinc finger 602-624 C2H2-type zinc finger 602-624 Zinc finger, C2H2 type 617-640 Zinc-finger double domain |
| Sequence: (in bold interface residues) | 1 MPGPPRSLEMGLLTFRDVAIEFSLEEWQHLDIAQQNLYRNVMLENYRNLAFLGIAVSKPD 60 61 LITCLEQGKEPWNMKRHEMVDEPPGMCPHFAQDLWPEQGMEDSFQKAILRRYGKYGHENL 120 121 QLRKGCKSVDEYKVNKEGYNGLNQCFTTAQSKVFQCDKYLKVFYKFLNSNRPKIRHTEKK 180 181 SFKCKKRVKLFCMLSHKTQHKSIYHREKSYKCKECGKTFNWSSTLTNHRKIYTEEKPYKC 240 241 EEYNKSPKQLSTLTTHEIIHAGEKLYKCEECGEAFNRSSNLTTHKIIHTGEKPYKCEECG 300 301 KAFIWSSTLTEHKKIHTRKKPYKCEECGKAFIWSSTLTRHKRMHTGEKPYKCEECGKAFS 360 361 QSSTLTTHKIIHTGEKRYKCLECGKAFKQLSTLTTHKIIHVGEKLYKCEECGKGFNRSSN 420 421 LTTHKIIHTGEKPYKCEECGKAFIWSSTLTKHKRIHTREKPYKCEECGKAFIWSSTLTRH 480 481 KRMHTGEKPYKCEECGKSFSQSSTLTTHKIIHTGEKPYKCEECGKAFNWSSTLTKHKIIH 540 541 TEEKPYKCEKCGKAFKQSSILTNHKRIHTGEKPYKCEECGKSFNRSSTFTKHKVIHTGVK 600 601 PYKCEECGKAFFWSSTLTKHKRIHTGEQPYKWEKFGKAFNRSSHLTTDKITHWREILQV |
| Interface Residues: | 249, 251, 255, 276, 277, 280, 283, 287, 305, 306, 307, 308, 311, 315, 332, 333, 335, 336, 338, 339, 361, 362, 363, 364, 366, 367, 388, 389, 390, 391, 392, 394, 395, 416, 417, 418, 419, 420, 423, 444, 445, 446, 447, 448, 450, 451, 453, 454, 455, 457, 471, 472, 473, 474, 475, 476, 479, 480, 483, 490, 500, 501, 502, 503, 504, 505, 506, 507, 508, 528, 529, 530, 531, 532, 535, 537, 557, 558, 559, 560, 562, 563, 584, 585, 587, 588, 589, 591, 612, 613, 614, 615, 616, 619 |
| 3D-footprint Homologues: | 7w1m_H, 8ssq_A, 5kkq_D, 2i13_A, 6e94_A, 3uk3_C, 8cuc_F, 7y3l_A, 5v3j_F, 8gn3_A, 7txc_E, 2lt7_A, 1tf3_A, 2drp_D, 6jnm_A, 5ei9_F, 5und_A, 8ssu_A, 6ml4_A, 6wmi_A, 7eyi_G, 6a57_A, 2jpa_A, 1ubd_C, 7n5w_A, 1mey_C, 1f2i_J, 5k5i_A, 2gli_A, 1g2f_F, 1tf6_A, 6u9q_A, 4x9j_A, 5kl3_A, 2wbs_A, 4m9v_C, 8h9h_G, 7y3m_I, 5yel_A, 2kmk_A, 7ysf_A, 6blw_A, 1llm_D, 5yj3_D |
| Binding Motifs: | UN0169.1 GCYTAGCCTCCCAGC |
| Binding Sites: | UN0169.1.1 UN0169.1.10 / UN0169.1.14 UN0169.1.11 / UN0169.1.16 UN0169.1.12 / UN0169.1.17 UN0169.1.13 / UN0169.1.18 UN0169.1.14 / UN0169.1.19 UN0169.1.15 / UN0169.1.20 UN0169.1.16 UN0169.1.17 UN0169.1.18 UN0169.1.19 UN0169.1.2 UN0169.1.20 UN0169.1.3 UN0169.1.4 / UN0169.1.6 UN0169.1.5 / UN0169.1.7 UN0169.1.6 / UN0169.1.9 UN0169.1.10 / UN0169.1.7 UN0169.1.11 / UN0169.1.8 UN0169.1.13 / UN0169.1.9 UN0169.1.12 UN0169.1.15 UN0169.1.4 UN0169.1.5 UN0169.1.8 |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.