Transcription Factor

Accessions: 4kfc_A (3D-footprint 20231221)
Names: KDP operon transcriptional regulatory protein KdpE, KDPE_ECOLI
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P21866
Length: 223
Pfam Domains: 5-113 Response regulator receiver domain
146-221 Transcriptional regulatory protein, C terminal
Sequence:
(in bold interface residues)
1 AMANVLIVEDEQAIRRFLRTALEGDGMRVFEAETLQRGLLEAATRKPDLIILDLGLPDGD 60
61 GIEFIRDLRQWSAVPVIVLSARSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRH 120
121 SAPDPLVKFSDVTVDLAARVIHRGEEEVHLTPIEFRLLAVLLNNAGKVLTQRQLLNQVWG 180
181 PNAVEHSHYLRIYMGHLRQKLEQDPARPRHFITATGIGYRFML
Interface Residues: 187, 188, 189, 191, 192, 193, 195, 196, 215
3D-footprint Homologues: 8jo2_H, 8hml_B, 4kfc_B, 7e1b_B, 4nhj_A, 5ed4_A, 8hih_Q, 2z33_A, 6lxn_A, 8b4b_W
Binding Motifs: 4kfc_AB TGTAAaannnnTnnaAAA
Publications: Narayanan A, Kumar S, Evrard A.N, Paul L.N, Yernool D.A. An asymmetric heterodomain interface stabilizes a response regulator-DNA complex. Nature communications 5:3282 (2014). [Pubmed]
Related annotations: PaperBLAST

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