Transcription Factor
| Accessions: | UP00124A (UniPROBE 20160601) |
| Names: | homeodomain transcription factor, IDX-1, insulin promoter factor 1, IPF-1, Ipf1, Islet/duodenum homeobox 1, Mody4, Pancreas/duodenum homeobox 1, pdx-1, Pdx1, Somatostatin-transactivating factor 1, STF-1 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P52946 |
| Description: | insulin promoter factor 1, homeodomain transcription factor |
| Length: | 93 |
| Pfam Domains: | 17-73 Homeobox domain |
| Sequence: (in bold interface residues) | 1 KGQWAGGAYTAEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHI 60 61 KIWFQNRRMKWKKEEDKKRSSGTPSGGGGGEEP |
| Interface Residues: | 17, 18, 19, 20, 58, 59, 61, 62, 65, 66, 69, 70, 73 |
| 3D-footprint Homologues: | 3d1n_M, 1ig7_A, 6a8r_A, 2h1k_B, 1puf_A, 3cmy_A, 5zfz_A, 1fjl_B, 1nk2_P, 1zq3_P, 1jgg_B, 3lnq_A, 2lkx_A, 6m3d_C, 5flv_I, 2hos_A, 1b72_A, 5zjt_E, 4cyc_A, 7psx_B, 5hod_A, 3l1p_A, 2ld5_A, 3a01_E, 7q3o_C, 5jlw_D, 6es3_K, 4xrs_G, 2hdd_A, 1au7_A, 3rkq_B, 2r5y_A, 2xsd_C, 1e3o_C, 1le8_A, 7xrc_C, 1o4x_A, 1du0_A, 4qtr_D, 1puf_B |
| Binding Motifs: | UP00124A_1 marsTAATTAgywcAt |
| Binding Sites: | GGTAATTA ACTAATTA AGTAATTA ATAATTAA ATAATTAG ATTAATGA ATTAATTA CCTAATTA CTAATTAA CTAATTAC CTAATTAG CTCATTAA CTTAATTA GATAATTA GCTAATTA GTAATTAA GTAATTAC GTCATTAA GTTAATTA TTAATTAA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.