Transcription Factor

Accessions: UP00450A (UniPROBE 20160601)
Names: None, PFL1900w_D1, putative, transcription factor with AP2 domain(s)
Organisms: Plasmodium falciparum
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Description: transcription factor with AP2 domain(s), putative: putative Plasmodium falciparum transcription factor, AP2 domain
Length: 115
Pfam Domains: 48-96 AP2 domain
Sequence:
(in bold interface residues)
1 KNEIDIKVCTLINCPTHNPQNYVKSNGKRGESLGDGMELKEENDDLKRIPGVYYDKNSQR 60
61 WFGEHKINGVKCAQSFAVKKHGCEEAKRLAIEWKKARIRGEVWDRFINKKKKNTN
Interface Residues: 45, 48, 49, 51, 52, 61, 82, 83, 86
3D-footprint Homologues: 4iri_A, 8ffi_L, 1o4x_B
Binding Motifs: UP00450A_1 rhycmaatTCTAyAwwmssbkw
Binding Sites: TATAGAAA
ATTCTATA
TCTATAAA
TTATAGAA
ATAGAAAA
ATATAGAA
ATCCTATA
ATCTATAA
ATGTAGAA
CATGTAGA
CTACAAAA
CTATAGAA
CTTATAGA
CTTCTACA
CTTCTATA
TCCTATAA
TCTACAAA
TCTATAGA
TGTAGAAA
TTCTACAA
Publications: Campbell TL, De Silva EK, Olszewski KL, Elemento O, Llinás M. Identification and genome-wide prediction of DNA binding specificities for the ApiAP2 family of regulators from the malaria parasite. PLoS Pathog : (2010). [Pubmed]
Related annotations: PaperBLAST

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