Transcription Factor

						

			
Accessions: UP00043A (UniPROBE 20160601)

			
Names: B-cell CLL/lymphoma 6, B-cell CLL/lymphoma 6 member B protein, Bazf, Bcl6-associated zinc finger protein, Bcl6b, member B
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: O88282
Description: B-cell CLL/lymphoma 6, member B: Mus musculus B-cell CLL/lymphoma 6, member B, mRNA
Length: 166
Pfam Domains:     15-38 C2H2-type zinc finger
    16-38 Zinc finger, C2H2 type
    16-38 C2H2-type zinc finger
    30-54 Zinc-finger double domain
    44-64 C2H2-type zinc finger
    44-62 Zinc-finger of C2H2 type
    44-55 C2H2-type zinc finger
    44-66 Zinc finger, C2H2 type
    58-82 Zinc-finger double domain
    71-82 C2H2-type zinc finger
    72-94 C2H2-type zinc finger
    72-94 Zinc finger, C2H2 type
   86-111 Zinc-finger double domain
  100-122 Zinc finger, C2H2 type
  100-122 C2H2-type zinc finger
  100-115 C2H2-type zinc finger
  115-138 Zinc-finger double domain
  128-150 Zinc-finger of C2H2 type
  128-151 C2H2-type zinc finger
Sequence: 
(in bold interface residues)		   1 SSGLELLAPGDEDKPYKCQLCRSAFRYKGNLASHRTVHTGEKPYRCSICGARFNRPANLK   60
  61 THSRIHSGEKPYKCETCGSRFVQVAHLRAHVLIHTGEKPYPCPTCGTRFRHLQTLKSHVR  120
 121 IHTGEKPYHCDPCGLHFRHKSQLRLHLRQKHGAATNTKVRYHILGG
Interface Residues: 26, 27, 28, 29, 30, 32, 33, 35, 36, 37, 39, 44, 54, 55, 56, 57, 58, 60, 61, 65, 82, 83, 84, 85, 86, 88, 89, 110, 111, 112, 113, 114, 116, 117, 118, 120, 138, 139, 140, 141, 142, 143, 144, 145, 146
3D-footprint Homologues: 7w1m_H, 7y3l_A, 5v3j_F, 7n5w_A, 5kkq_D, 6wmi_A, 8ssq_A, 5und_A, 8ssu_A, 2gli_A, 8gn3_A, 8h9h_G, 7eyi_G, 7y3m_I, 2i13_A, 5yel_A, 2jpa_A, 1ubd_C, 2kmk_A, 6jnm_A, 8cuc_F, 1tf3_A, 1tf6_A, 6u9q_A, 4x9j_A, 1llm_D, 5kl3_A, 5ei9_F, 1mey_C, 1f2i_J, 5k5i_A, 6ml4_A, 1g2f_F, 6blw_A, 2lt7_A, 6e94_A, 7ysf_A, 7txc_E, 5yj3_D, 2drp_D, 6a57_A, 3uk3_C, 2wbs_A, 4m9v_C
Binding Motifs: UP00043A_1 wcTTTCkAGGAAttys
UP00043A_2 hbscCCgCCCCwhmwm
Binding Sites: ACCCCGCC
ACTAGAAA
ACTTTCTA
AGGGGCGG
ATTTCTAG
CCCACCCC
CCGCCCCA
CCGCCCCG
CCTAGAAA
CCTCGAAA
CTAGAAAG
CTTTCTAA
GCCCACCC
GCTTTCTA
GGCGGGGA
TCCAGGAA
TCCTAGAA
TCGAGGAA
TCTAAGAA
TCTAGGAA
			
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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