Transcription Factor
| Accessions: | UP00248A (UniPROBE 20160601) |
| Names: | paired box gene 7, Paired box protein Pax-7, Pax7 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P47239 |
| Description: | paired box gene 7 |
| Length: | 274 |
| Pfam Domains: | 16-141 'Paired box' domain 198-254 Homeobox domain 221-251 Homeobox KN domain |
| Sequence: (in bold interface residues) | 1 NYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRV 60 61 SHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLL 120 121 KDGHCDRSTVPSVSSISRVLRIKFGKKEDDEEGDKKEEDGEKKAKHSIDGILGDKGNRLD 180 181 EGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEAR 240 241 VQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPP |
| Interface Residues: | 29, 61, 62, 64, 66, 67, 83, 86, 89, 132, 133, 134, 135, 137, 138, 141, 197, 198, 199, 200, 201, 239, 240, 242, 243, 246, 247, 249, 250, 251, 253, 254 |
| 3D-footprint Homologues: | 1k78_A, 1pdn_C, 6pax_A, 4j19_B, 1fjl_B, 3cmy_A, 1ig7_A, 6a8r_A, 3d1n_M, 2h1k_B, 1puf_A, 5zfz_A, 3lnq_A, 1nk2_P, 6m3d_C, 1zq3_P, 1jgg_B, 2lkx_A, 7q3o_C, 2ld5_A, 3a01_E, 2hdd_A, 5flv_I, 2r5y_A, 1puf_B, 5zjt_E, 1b72_A, 2hos_A, 5hod_A, 3rkq_B, 5jlw_D, 4cyc_A, 6es3_K, 4xrs_G, 3l1p_A, 7psx_B, 1au7_A, 2xsd_C, 7xrc_C, 1le8_A, 1e3o_C, 1mnm_C, 6fqq_E, 4qtr_D, 1du0_A, 4xrm_B, 8g87_X, 1le8_B, 1k61_B, 2ypa_A |
| Binding Motifs: | UP00248A_1 mgwmyTAATTArkwmda |
| Binding Sites: | AATAATTA AATTAATA ACTAATTA ATAATTAA ATAATTAC ATAATTAG ATAATTAT ATAATTGA ATCAATTA ATTAATTA ATTAATTG CAATTATC CATAATTA CTAATTAA CTAATTAG CTTAATTA GATAATTA GCTAATTA GTTAATTA TAATTATA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.