Transcription Factor
Accessions: | 1qp9_B (3D-footprint 20231221) |
Names: | CYP1 activatory protein, CYP1(HAP1-PC7) ACTIVATORY PROTEIN, HAP1_YEASX, Heme activator protein 1, Heme-responsive zinc finger transcription factor HAP1 |
Organisms: | Saccharomyces cerevisiae |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Uniprot: | P0CS82 |
Length: | 74 |
Pfam Domains: | 8-42 Fungal Zn(2)-Cys(6) binuclear cluster domain |
Sequence: (in bold interface residues) | 1 KRNRIPLGCTICRKRKVKCDKLRPHCQQCTKTGVAHLCHYMEQTWAEEAEKELLKDNELK 60 61 KLRERVKSLEKTLS |
Interface Residues: | 15, 16, 17, 18, 20, 21, 24 |
3D-footprint Homologues: | 6o19_A, 2er8_C, 1hwt_C, 1pyi_A, 7uik_T, 1zme_D, 1d66_B, 3coq_A, 6gys_C, 7y3l_A, 7eyi_G, 8h9h_G, 7n5w_A |
Binding Motifs: | 1qp9_AB CGCnnnTATCGCnnnTAG 1qp9_B ATAnnnGCG |
Binding Sites: | 1qp9_E 1qp9_F |
Publications: | Lukens A.K, King D.A, Marmorstein R. Structure of HAP1-PC7 bound to DNA: implications for DNA recognition and allosteric effects of DNA-binding on transcriptional activation. Nucleic acids research 28:3853-63 (2000). [Pubmed] |
Related annotations: | PaperBLAST |
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