Transcription Factor
| Accessions: | Q6NX49 (JASPAR 2024) |
| Names: | ZN544_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q6NX49 |
| Length: | 715 |
| Pfam Domains: | 14-54 KRAB box 370-390 Zinc-finger double domain 380-402 Zinc finger, C2H2 type 380-402 C2H2-type zinc finger 380-393 C2H2-type zinc finger 395-419 Zinc-finger double domain 407-428 C2H2-type zinc finger 408-430 Zinc finger, C2H2 type 408-430 C2H2-type zinc finger 425-445 Zinc-finger double domain 436-456 C2H2-type zinc finger 436-458 Zinc finger, C2H2 type 450-474 Zinc-finger double domain 463-486 C2H2-type zinc finger 464-486 C2H2-type zinc finger 464-486 Zinc finger, C2H2 type 479-502 Zinc-finger double domain 492-513 C2H2-type zinc finger 492-514 C2H2-type zinc finger 492-514 Zinc finger, C2H2 type 507-530 Zinc-finger double domain 519-540 C2H2-type zinc finger 520-542 C2H2-type zinc finger 520-542 Zinc finger, C2H2 type 537-557 Zinc-finger double domain 548-570 Zinc finger, C2H2 type 562-586 Zinc-finger double domain 576-598 C2H2-type zinc finger 576-598 Zinc finger, C2H2 type 576-598 C2H2-type zinc finger 591-614 Zinc-finger double domain 603-624 C2H2-type zinc finger 604-626 C2H2-type zinc finger 604-626 Zinc finger, C2H2 type 619-642 Zinc-finger double domain 631-654 C2H2-type zinc finger 632-654 C2H2-type zinc finger 632-654 Zinc finger, C2H2 type 647-670 Zinc-finger double domain 660-679 C2H2-type zinc finger 660-682 Zinc finger, C2H2 type 660-678 C2H2-type zinc finger 674-698 Zinc-finger double domain 687-710 C2H2-type zinc finger 688-710 C2H2-type zinc finger 688-710 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MEARSMLVPPQASVCFEDVAMAFTQEEWEQLDLAQRTLYREVTLETWEHIVSLGLFLSKS 60 61 DVISQLEQEEDLCRAEQEAPRDWKATLEENRLNSEKDRAREELSHHVEVYRSGPEEPPSL 120 121 VLGKVQDQSNQLREHQENSLRFMVLTSERLFAQREHCELELGGGYSLPSTLSLLPTTLPT 180 181 STGFPKPNSQVKELKQNSAFINHEKNGADGKHCESHQCARAFCQSIYLSKLGNVETGKKN 240 241 PYEYIVSGDSLNYGSSLCFHGRTFSVKKSDDCKDYGNLFSHSVSLNEQKPVHFGKSQYEC 300 301 DECRETCSESLCLVQTERSGPGETPFRCEERCAAFPMASSFSDCNIIQTTEKPSVCNQCG 360 361 KSFSCCKLIHQRTHTGEKPFECTQCGKSFSQSYDLVIHQRTHTGEKPYECDLCGKSFTQR 420 421 SKLITHQRIHTGEKPYQCIECRKSFRWNSNLIVHQRIHTGEKPYECTHCGKSFSQSYELV 480 481 THKRTHTGEKPFKCTQCGKSFSQKYDLVVHQRTHTGEKPYECNLCGKSFSQSSKLITHQR 540 541 IHTGEKPYQCIECGKSFRWNSNLVIHQRIHTGEKPYDCTHCGKSFSQSYQLVAHKRTHTG 600 601 EKPYECNECGKAFNRSTQLIRHLQIHTGEKPYKCNQCNKAFARSSYLVMHQRTHTGEKPF 660 661 ECSQCGKAFSGSSNLLSHHRIHSGEKPYECSDCGKSFRQQSQLVVHRRTHTGEKP |
| Interface Residues: | 390, 391, 393, 394, 397, 418, 419, 421, 422, 424, 425, 447, 448, 449, 450, 453, 457, 464, 474, 475, 476, 477, 478, 480, 481, 502, 503, 504, 505, 506, 508, 509, 531, 532, 533, 534, 537, 540, 558, 559, 560, 561, 562, 565, 568, 587, 588, 589, 590, 591, 592, 593, 594, 595, 596, 599, 613, 614, 615, 616, 617, 618, 619, 620, 621, 622, 625, 642, 643, 644, 645, 646, 649, 670, 671, 672, 673, 674, 677, 680 |
| 3D-footprint Homologues: | 8cuc_F, 3uk3_C, 8ssq_A, 7w1m_H, 8ssu_A, 5kkq_D, 8gn3_A, 6jnm_A, 6a57_A, 2kmk_A, 7y3l_A, 5v3j_F, 5k5l_F, 1tf6_A, 1g2f_F, 5yel_A, 7n5w_A, 2gli_A, 5ei9_F, 5k5i_A, 8h9h_G, 7ysf_A, 1ubd_C, 6ml4_A, 7txc_E, 6e94_A, 6blw_A, 6u9q_A, 1llm_D, 4m9v_C, 2jpa_A, 1tf3_A, 4x9j_A, 1f2i_J, 2wbs_A, 5yj3_D, 5kl3_A, 2lt7_A, 2drp_D, 7y3m_I |
| Binding Motifs: | UN0629.1 twcyTGGCAcwgTGCCArgwa UN0629.2 yTGGCAcwgTGCCAr |
| Binding Sites: | UN0629.1.2 UN0629.1.3 UN0629.1.18 UN0629.1.19 UN0629.1.20 UN0629.1.4 UN0629.1.7 UN0629.1.8 UN0629.1.13 UN0629.1.14 UN0629.1.17 UN0629.1.15 UN0629.1.16 UN0629.1.1 UN0629.1.10 UN0629.1.11 UN0629.1.12 UN0629.1.5 UN0629.1.6 UN0629.1.9 UN0629.2.1 UN0629.2.10 UN0629.2.11 UN0629.2.12 UN0629.2.13 UN0629.2.14 UN0629.2.15 UN0629.2.16 UN0629.2.17 UN0629.2.18 UN0629.2.19 UN0629.2.2 UN0629.2.20 UN0629.2.3 UN0629.2.4 UN0629.2.5 UN0629.2.6 UN0629.2.7 UN0629.2.8 UN0629.2.9 |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.