Transcription Factor
Accessions: | 3m9e_B (3D-footprint 20231221) |
Names: | c-erbA-2, c-erbA-beta, Nuclear receptor subfamily 1 group A member 2, THB_RAT, Thyroid hormone receptor beta |
Organisms: | Rattus norvegicus |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Uniprot: | P18113 |
Length: | 99 |
Pfam Domains: | 2-71 Zinc finger, C4 type (two domains) |
Sequence: (in bold interface residues) | 1 ELCVVCGDKATGYHYRCITCEGCKGFFRRTIQKSLHPSYSCKYEGKCIIDKVTRNQCQEC 60 61 RFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREE |
Interface Residues: | 11, 12, 14, 15, 21, 22, 24, 25, 28, 29, 55, 79, 81, 84 |
3D-footprint Homologues: | 6fbq_A, 7wnh_D, 6l6q_B, 1lo1_A, 3g9m_B, 1a6y_A, 4oln_B, 4umm_E, 3cbb_A, 8cef_H, 4iqr_B, 2han_A, 1hcq_E, 8hbm_B, 5krb_G, 2han_B, 1kb2_B, 2a66_A, 2nll_B, 1lat_A, 7xv6_B, 2ff0_A, 1dsz_A, 5emc_A, 7prw_B, 5cbx_B, 3g6t_A, 1r4i_A, 5cbz_E, 4tnt_B, 5e69_A, 4hn5_B |
Binding Motifs: | 3m9e_AB TGACCtnnnnnnrGGTCA |
Binding Sites: | 3m9e_C / 3m9e_D |
Publications: | Chen Y, Young M.A. Structure of a thyroid hormone receptor DNA-binding domain homodimer bound to an inverted palindrome DNA response element. Molecular endocrinology (Baltimore, Md.) 24:1650-64 (2010). [Pubmed] |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.