Transcription Factor
| Accessions: | T049112_1.02 (CISBP 1.02), Q99JB0 (JASPAR 2024) |
| Names: | Klf7, T049112_1.02;, KLF7_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | experiment type:PBM, family:C2H2 ZF |
| Length: | 301 |
| Pfam Domains: | 218-242 C2H2-type zinc finger 218-242 Zinc finger, C2H2 type 234-255 Zinc-finger double domain 248-272 C2H2-type zinc finger 248-272 Zinc finger, C2H2 type 265-288 Zinc-finger double domain 278-300 C2H2-type zinc finger 278-300 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MDVLASYSIFQELQLVHDTGYFSALPSLEETWQQTCLELERYLQTEPRRISETFGEDLDC 60 61 FLHASPPPCIEESFRRLDPLLLPVEATICEKSSAVDILLSRDKLLSETCLSLQPTSSSLD 120 121 SYTAVNQAQLNAVTSLTPPSSPELSRHLVKTSQTLSAVDGTVTLKLVAKKASLSSVKVGG 180 181 VAAAAAVTPAGAVKSGQSDSEQGGGGADTCPENKKRVHRCQFNGCRKVYTKSSHLKAHQR 240 241 THTGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKRH 300 301 I |
| Interface Residues: | 230, 231, 232, 233, 234, 236, 237, 239, 240, 243, 259, 260, 261, 262, 263, 264, 266, 267, 268, 271, 288, 289, 290, 291, 292, 293, 295, 296, 299 |
| 3D-footprint Homologues: | 6jnm_A, 3uk3_C, 1tf3_A, 6ml4_A, 5v3j_F, 7n5w_A, 5kl3_A, 1ubd_C, 7ysf_A, 6wmi_A, 5ei9_F, 1mey_C, 7eyi_G, 2kmk_A, 2gli_A, 1g2f_F, 6blw_A, 1tf6_A, 6u9q_A, 2i13_A, 8h9h_G, 6e94_A, 5und_A, 5kkq_D, 2lt7_A, 7y3m_I, 6a57_A, 2jpa_A, 5k5i_A, 7w1m_H, 8cuc_F, 7y3l_A, 4m9v_C, 2wbs_A, 8ssq_A, 2drp_D, 1f2i_J, 8gn3_A, 5yel_A, 4x9j_A, 1llm_D, 7txc_E, 5yj3_D |
| Binding Motifs: | PB0039.1 tyrrCCmCGCCChyww PB0143.1 varywTACGCCChamwk M0405_1.02 dGGGcGkggc |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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