Transcription Factor

						

			
Accessions: 5yej_C (3D-footprint 20231221)

			
Names: A0QX69_MYCS2, TetR family transcriptional regulator
Organisms: Mycobacterium smegmatis, Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: A0QX69
Length: 169
Pfam Domains:      8-53 Bacterial regulatory proteins, tetR family
   67-150 Tetracyclin repressor, C-terminal all-alpha domain
Sequence: 
(in bold interface residues)		   1 QLHKPDVVAAATKILDDHGIADLTMRRLARELDVTPGALYWHFANKQELLGAVADHILRT   60
  61 ARTDTADLAWREQIHESCRALRDALLSHTDGAELVSASFASGQSVVITEIVEQLGRAARA  120
 121 AGVSDADVDAAARTVIYYVLGFTVDEQSRLQWRQFRFGLQLLVDGLAAH
Interface Residues: 25, 26, 35, 36, 37, 38, 40, 41, 57, 59, 61, 63, 64, 66, 68
3D-footprint Homologues: 4gck_A, 5vl9_A, 1jt0_C, 6gy3_A, 5yej_B, 5gpc_B, 3zql_B, 5haw_A, 6c31_A, 1qpi_A, 4pxi_B, 7jnp_A, 6o6p_B, 6wpa_A, 6yl2_A, 6bhx_B
Binding Motifs: 5yej_BC CTTGAACGnTGTTCnnG
Binding Sites: 5yej_D
5yej_F
			
Publications: Yan L, Tang Q, Guan Z, Pei K, Zou T, He J. Structural insights into operator recognition by BioQ in the Mycobacterium smegmatis biotin synthesis pathway. Biochim Biophys Acta Gen Subj 1862:1843-1851 (2018). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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