Transcription Factor

Accessions: 1hlo_B (3D-footprint 20231221)
Names: bHLHd4, Class D basic helix-loop-helix protein 4, MAX_HUMAN, Myc-associated factor X, Protein max, TRANSCRIPTION FACTOR MAX
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P61244
Length: 73
Pfam Domains: 5-55 Helix-loop-helix DNA-binding domain
Sequence:
(in bold interface residues)
1 SDADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNH 60
61 THQQDIDDLKRQN
Interface Residues: 6, 8, 9, 10, 12, 13, 16, 17, 21, 41
3D-footprint Homologues: 1a0a_B, 7z5k_B, 1an4_A, 7rcu_E, 5gnj_I, 6g1l_A, 4h10_B, 7ssa_L, 5i50_B, 1am9_A, 8osl_O, 7d8t_A, 4zpk_A, 7xi3_A, 5nj8_D, 7f2f_B, 5eyo_A, 7xq5_A, 5v0l_A, 4h10_A
Binding Motifs: 1hlo_B cGtGG
1hlo_AB CCaCGtG
Binding Sites: 1hlo_C
1hlo_D
Publications: Brownlie P, Ceska T, Lamers M, Romier C, Stier G, Teo H, Suck D. The crystal structure of an intact human Max-DNA complex: new insights into mechanisms of transcriptional control. Structure (London, England : 1993) 5:509-20 (1997). [Pubmed]
Related annotations: PaperBLAST

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