Transcription Factor
| Accessions: | 1svc_P (3D-footprint 20231221) |
| Names: | DNA-binding factor KBF1, EBP-1, NFKB1_HUMAN, NUCLEAR FACTOR KAPPA-B (NF-KB), Nuclear factor NF-kappa-B p105 subunit, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | P19838 |
| Length: | 311 |
| Pfam Domains: | 3-201 Rel homology domain (RHD) |
| Sequence: (in bold interface residues) | 1 PYLQILEQPKQRGFRFRYVAEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVT 60 61 NGKNIHLHAHSLVGKHCEDGICTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTEAC 120 121 IRGYNPGLLVHPDLAYLQAEGGGDRQLGDREKELIRQAALQQTKEMDLSVVRLMFTAFLP 180 181 DSTGSFTRRLEPVVSDAIYDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQ 240 241 IRFYEEEENGGVWEGFGDFSPTDVHRQFAIVFKTPKYKDINITKPASVFVQLRRKSDLET 300 301 SEPKPFLYYPE |
| Interface Residues: | 15, 17, 18, 20, 21, 23, 24, 25, 202, 204, 233, 266, 293, 294 |
| 3D-footprint Homologues: | 1a3q_A, 2o61_A, 1gji_A, 2ram_A, 1nfk_A, 7cli_B, 1p7h_L |
| Binding Motifs: | 1svc_P gnnTCCc |
| Binding Sites: | 1svc_D |
| Publications: | Mueller C. W., Rey F. A., Sodeoka M., Verdine G. L., Harrison S. C. Structure of the NF-kappaB p50 homodimer bound to DNA. Nature 373:311-317 (1995). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.