Transcription Factor

Accessions: T134803_1.02 (CISBP 1.02)
Names: Estrogen_receptor, T134803_1.02;
Organisms: Aplysia californica
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:Nuclear receptor
Length: 477
Pfam Domains: 83-151 Zinc finger, C4 type (two domains)
216-401 Ligand-binding domain of nuclear hormone receptor
Sequence:
(in bold interface residues)
1 MVSPSPCMPVLPLSGAGGGGEGTAGSAHLQAATSTTPEAGSGTLPHNFLMDVHGPGTLGA 60
61 SPSSHMKQEVGGAVPGSSIQAKLCQVCSDNASGFHYGVWSCEGCKAFFKRSIQGPVDYIC 120
121 PATNTCTIDKHRRKSCQACRLRRCYEVGMNKGSQRKEKRNSGNTSSLKGKRCRADSSDSA 180
181 VNSTNNGASSSKSSKRSRSASILEALQKADLPVMDSYHNHNLPATRVHLLNTLIKLADRE 240
241 LVYLINWAKHVPGYTCLTLGDQVHLIECCWMELLLLNCAFRSMEHEGRTLVFAPDFHLER 300
301 QQWALTGMGDVLEQVSAVSEQMLLHGLNKEELLLLQATVLVNAEVRPLDSFLKIQEMRQL 360
361 ILDVFMEVAGRHQGFGNWRHAPSILLLLTHIRQAGERGITYFQKLKMEGCVTFCDLLTEM 420
421 LDAHNSSGERRRLQQQQQQPQQQSHAHHHHPPPPLPHHHHHSTQSSPQHSRAFPYHH
Interface Residues: 75, 92, 93, 95, 96, 102, 103, 105, 106, 109, 110, 134, 158, 160, 171, 173, 185
3D-footprint Homologues: 3rnu_B, 6fbq_A, 7wnh_D, 6l6q_B, 3g9m_B, 1a6y_A, 1lo1_A, 4oln_B, 1kb2_B, 2a66_A, 8hbm_B, 5krb_G, 2nll_B, 1lat_A, 2ff0_A, 1dsz_A, 3cbb_A, 7xv6_B, 2han_A, 1hcq_E, 4umm_E, 8cef_H, 4iqr_B, 2han_B, 7prw_B, 5cbx_B, 5cbz_E, 4tnt_B, 5e69_A, 4hn5_B, 3g6t_A, 1r4i_A, 5emc_A
Binding Motifs: M1492_1.02 dTGACCyr
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.