Transcription Factor

						

			
Accessions: Q9H5H4 (JASPAR 2024)

			
Names: ZN768_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q9H5H4
Length: 540
Pfam Domains:     60-72 RNA polymerase Rpb1 C-terminal repeat 
  117-128 RNA polymerase Rpb1 C-terminal repeat 
  130-142 RNA polymerase Rpb1 C-terminal repeat 
  262-283 C2H2-type zinc finger
  263-283 Zinc finger, C2H2 type
  263-281 C2H2-type zinc finger
  278-299 Zinc-finger double domain
  288-311 C2H2-type zinc finger
  289-311 C2H2-type zinc finger
  289-311 Zinc finger, C2H2 type
  304-327 Zinc-finger double domain
  316-339 C2H2-type zinc finger
  317-339 C2H2-type zinc finger
  317-339 Zinc finger, C2H2 type
  332-354 Zinc-finger double domain
  344-369 C2H2-type zinc finger
  345-367 C2H2-type zinc finger
  345-367 Zinc finger, C2H2 type
  360-383 Zinc-finger double domain
  373-395 C2H2-type zinc finger
  373-395 Zinc finger, C2H2 type
  387-411 Zinc-finger double domain
  401-423 C2H2-type zinc finger
  401-423 C2H2-type zinc finger
  401-423 Zinc finger, C2H2 type
  419-439 Zinc-finger double domain
  429-451 Zinc finger, C2H2 type
  429-451 C2H2-type zinc finger
  429-439 C2H2-type zinc finger
  444-467 Zinc-finger double domain
  456-479 C2H2-type zinc finger
  457-479 C2H2-type zinc finger
  457-479 Zinc finger, C2H2 type
  457-479 Zinc-finger of C2H2 type
  474-494 Zinc-finger double domain
  485-507 C2H2-type zinc finger
  485-507 Zinc finger, C2H2 type
  500-523 Zinc-finger double domain
  512-535 C2H2-type zinc finger
  513-535 C2H2-type zinc finger
  513-535 Zinc finger, C2H2 type
Sequence: 
(in bold interface residues)		   1 MEREALPWGLEPQDVQSSDEMRSPEGYLRGNMSENEEEEISQQEGSGDYEVEEIPFGLEP   60
  61 QSPGFEPQSPEFEPQSPRFEPESPGFESRSPGLVPPSPEFAPRSPESDSQSPEFESQSPR  120
 121 YEPQSPGYEPRSPGYEPRSPGYESESSRYESQNTELKTQSPEFEAQSSKFQEGAEMLLNP  180
 181 EEKSPLNISVGVHPLDSFTQGFGEQPTGDLPIGPPFEMPTGALLSTPQFEMLQNPLGLTG  240
 241 ALRGPGRRGGRARGGQGPRPNICGICGKSFGRGSTLIQHQRIHTGEKPYKCEVCSKAFSQ  300
 301 SSDLIKHQRTHTGERPYKCPRCGKAFADSSYLLRHQRTHSGQKPYKCPHCGKAFGDSSYL  360
 361 LRHQRTHSHERPYSCTECGKCYSQNSSLRSHQRVHTGQRPFSCGICGKSFSQRSALIPHA  420
 421 RSHAREKPFKCPECGKRFGQSSVLAIHARTHLPGRTYSCPDCGKTFNRSSTLIQHQRSHT  480
 481 GERPYRCAVCGKGFCRSSTLLQHHRVHSGERPYKCDDCGKAFSQSSDLIRHQRTHAAGRR  540
Interface Residues: 271, 272, 273, 274, 275, 277, 278, 280, 281, 282, 284, 299, 300, 301, 302, 303, 305, 306, 327, 328, 329, 330, 331, 333, 334, 335, 337, 355, 356, 357, 358, 359, 360, 362, 363, 365, 366, 383, 384, 385, 386, 387, 389, 390, 411, 412, 413, 414, 415, 416, 417, 418, 422, 439, 440, 441, 442, 443, 446, 449, 467, 468, 469, 470, 471, 474, 480, 494, 495, 496, 498, 499, 502, 506, 523, 524, 525, 526, 527, 529, 530
3D-footprint Homologues: 6jnm_A, 3uk3_C, 7w1m_H, 6blw_A, 6u9q_A, 4x9j_A, 1f2i_J, 1tf6_A, 5k5i_A, 2kmk_A, 8ssq_A, 2lt7_A, 7ysf_A, 2jpa_A, 2gli_A, 5ei9_F, 5kl3_A, 1llm_D, 2drp_D, 6e94_A, 5yel_A, 8ssu_A, 5yj3_D, 6ml4_A, 5v3j_F, 4m9v_C, 5kkq_D, 8gn3_A, 8cuc_F, 7y3l_A, 1g2f_F, 7y3m_I, 7txc_E, 5k5l_F, 1ubd_C, 1tf3_A, 7n5w_A, 8h9h_G, 6a57_A, 2wbs_A
Binding Motifs: UN0341.1 rGCwCAGAGAGGTTaA
MA1731.1 yygcyyrsCcTCTCTGdk
MA1731.2 sCcTCTCTG
Binding Sites: UN0341.1.1
UN0341.1.10
UN0341.1.11
UN0341.1.12
UN0341.1.13
UN0341.1.14
UN0341.1.15
UN0341.1.16
UN0341.1.17
UN0341.1.18
UN0341.1.19
UN0341.1.2
UN0341.1.20
UN0341.1.3
UN0341.1.4
UN0341.1.5
UN0341.1.6
UN0341.1.7
UN0341.1.8
UN0341.1.9
			
Publications: Rohrmoser M, Kluge M, Yahia Y, Gruber-Eber A, Maqbool MA, Forné I, Krebs S, Blum H, Greifenberg AK, Geyer M, Descostes N, Imhof A, Andrau JC, Friedel CC, Eick D. MIR sequences recruit zinc finger protein ZNF768 to expressed genes. Nucleic Acids Res 47:700-715 (2019). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.