Transcription Factor

Accessions: 2stt_A (3D-footprint 20241219), 2stw_A (3D-footprint 20241219)
Names: ETS1_HUMAN, p54, Protein C-ets-1
Organisms: Homo sapiens
Libraries: 3D-footprint 20241219 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P14921
Length: 96
Pfam Domains: 16-96 Ets-domain
Sequence:
(in bold interface residues)
1 VIPAAALAGYTGSGPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRK 60
61 NKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFV
Interface Residues: 68, 69, 72, 73, 75, 76, 90
3D-footprint Homologues: 7jsa_J, 8ee9_F, 8smh_F, 8smj_F, 1yo5_C
Binding Motifs: 2stt_A cCGGa
2stw_A CCGg
Binding Sites: 2stt_B / 2stw_B
2stt_C / 2stw_C
Publications: Werner M.H, Clore G.M, Fisher C.L, Fisher R.J, Trinh L, Shiloach J, Gronenborn A.M. Correction of the NMR structure of the ETS1/DNA complex. Journal of biomolecular NMR 10:317-28 (1997). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.