Transcription Factor
| Accessions: | UP00416A (UniPROBE 20160601) |
| Names: | EWSR2, Fli-1, Fli1, Friend leukemia integration 1, Friend leukemia integration 1 transcription factor, Retroviral integration site protein Fli-1, SIC-1, Sic1 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q544B3 |
| Description: | Friend leukemia integration 1: Friend leukemia integration 1 transcription factor |
| Length: | 116 |
| Pfam Domains: | 16-98 Ets-domain |
| Sequence: (in bold interface residues) | 1 ILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGER 60 61 KSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPTETSMYK |
| Interface Residues: | 14, 69, 70, 72, 73, 74, 76, 77, 91 |
| 3D-footprint Homologues: | 3zp5_A, 3jtg_A, 1dux_F, 7jsa_J, 8ee9_F, 4mhg_A, 2stt_A, 4uno_A, 4l18_B, 4lg0_B, 1yo5_C, 4bqa_A, 1awc_A, 4iri_A, 1bc8_C |
| Binding Motifs: | UP00416A_1 mbsrAyTTCCGGtwky |
| Binding Sites: | AACCGGAA ACATCCGG ACCGGAAA ACCGGAAG ACCGGATG ACTTCCGG CACCGGAA CACTTCCG CATTTCCG CCGGAAAC CCGGAAGC CCGGATGC CGGAAGTA CTTCCGGA CTTCCGGC GACCGGAA GCCGGAAA TACCGGAA TCCGGAAA TTCCGGAA |
| Publications: | Wei G-H, Badis G, Berger MF, Kivioja T, Palin K, Enge M, Bonke M, Jolma A, Varjosalo M, Gehrke AR, Yan J, Talukder S, Turunen M, Taipale M, Stunnenberg HG, Ukkonen E, Hughes TR, Bulyk ML, Taipale J. Genome-wide analysis of ETS family DNA-binding in vitro and in vivo. The EMBO Journal. Epub 2010 Jun 1. doi:10.1038/emboj.2010.106 [Pubmed] |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.