Transcription Factor
| Accessions: | Q12901 (JASPAR 2024) |
| Names: | ZN155_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q12901 |
| Length: | 538 |
| Pfam Domains: | 8-48 KRAB box 176-198 C2H2-type zinc finger 176-198 Zinc finger, C2H2 type 193-214 Zinc-finger double domain 204-226 Zinc finger, C2H2 type 205-226 C2H2-type zinc finger 206-226 C2H2-type zinc finger 218-242 Zinc-finger double domain 232-254 C2H2-type zinc finger 232-254 C2H2-type zinc finger 232-254 Zinc finger, C2H2 type 246-270 Zinc-finger double domain 260-282 Zinc finger, C2H2 type 260-280 Zinc-finger of C2H2 type 275-298 Zinc-finger double domain 288-300 C2H2-type zinc finger 288-310 Zinc finger, C2H2 type 288-310 C2H2-type zinc finger 303-326 Zinc-finger double domain 316-338 C2H2-type zinc finger 316-334 C2H2-type zinc finger 316-338 Zinc finger, C2H2 type 330-353 Zinc-finger double domain 344-362 C2H2-type zinc finger 359-381 Zinc-finger double domain 372-394 C2H2-type zinc finger 372-382 C2H2-type zinc finger 372-394 Zinc finger, C2H2 type 387-411 Zinc-finger double domain 400-422 Zinc-finger of C2H2 type 400-422 C2H2-type zinc finger 400-423 C2H2-type zinc finger 400-422 Zinc finger, C2H2 type 415-439 Zinc-finger double domain 428-450 C2H2-type zinc finger 428-450 Zinc finger, C2H2 type 442-466 Zinc-finger double domain 456-478 C2H2-type zinc finger 456-481 C2H2-type zinc finger 456-478 Zinc finger, C2H2 type 473-492 Zinc-finger double domain |
| Sequence: (in bold interface residues) | 1 MTTFKEAVTFKDVAVVFTEEELGLLDPAQRKLYRDVMLENFRNLLSVGHQPFHQDTCHFL 60 61 REEKFWMMGTATQREGNSGGKIQTELESVPEAGAHEEWSCQQIWEQIAKDLTRSQDSIIN 120 121 NSQFFENGDVPSQVEAGLPTIHTGQKPSQGGKCKQSISDVPIFDLPQQLYSEEKSYTCDE 180 181 CGKSICYISALHVHQRVHVGEKLFMCDVCGKEFSQSSHLQTHQRVHTGEKPFKCEQCGKG 240 241 FSRRSALNVHRKLHTGEKPYICEACGKAFIHDSQLKEHKRIHTGEKPFKCDICGKTFYFR 300 301 SRLKSHSMVHTGEKPFRCDTCDKSFHQRSALNRHCMVHTGEKPYRCEQCGKGFIGRLDFY 360 361 KHQVVHTGEKPYNCKECGKSFRWSSCLLNHQRVHSGEKSFKCEECGKGFYTNSQLSSHQR 420 421 SHSGEKPYKCEECGKGYVTKFNLDLHQRVHTGERPYNCKECGKNFSRASSILNHKRLHCQ 480 481 KKPFKCEDCGKRLVHRTYRKDQPRDYSGENPSKCEDCGRRYKRRLNLDILLSLFLNDT |
| Interface Residues: | 187, 189, 192, 193, 195, 196, 199, 214, 215, 216, 217, 218, 220, 221, 222, 232, 242, 243, 244, 245, 246, 247, 248, 249, 250, 253, 270, 271, 272, 273, 274, 277, 280, 298, 299, 300, 301, 302, 304, 305, 326, 327, 328, 329, 330, 332, 333, 354, 355, 356, 357, 358, 359, 361, 383, 384, 385, 386, 389, 395, 409, 410, 411, 412, 413, 414, 417, 421, 438, 439, 440, 441, 442, 443, 445, 466, 467, 468, 469, 470, 472, 473 |
| 3D-footprint Homologues: | 7w1m_H, 2jpa_A, 7y3l_A, 7n5w_A, 3uk3_C, 1tf6_A, 4x9j_A, 1llm_D, 5kl3_A, 2drp_D, 1f2i_J, 6wmi_A, 1g2f_F, 8h9h_G, 4m9v_C, 7eyi_G, 2lt7_A, 6e94_A, 2kmk_A, 8cuc_F, 8ssu_A, 6blw_A, 5kkq_D, 2wbs_A, 6u9q_A, 7txc_E, 5yj3_D, 5k5i_A, 8ssq_A, 2gli_A, 1ubd_C, 1tf3_A, 6ml4_A, 5v3j_F, 8gn3_A, 5und_A, 7ysf_A, 5k5l_F, 5yel_A, 5ei9_F, 2i13_A, 1mey_C, 6jnm_A, 7y3m_I, 6a57_A |
| Binding Motifs: | UN0600.1 twcYTGGCAccgTGCCARgwa UN0600.2 YTGGCAccgTGCCARg |
| Binding Sites: | UN0600.1.1 UN0600.1.10 / UN0600.1.14 UN0600.1.11 / UN0600.1.15 UN0600.1.12 / UN0600.1.16 UN0600.1.13 / UN0600.1.17 UN0600.1.14 / UN0600.1.18 UN0600.1.15 / UN0600.1.20 UN0600.1.16 UN0600.1.17 UN0600.1.18 UN0600.1.19 UN0600.1.2 UN0600.1.20 UN0600.1.3 / UN0600.1.5 UN0600.1.4 / UN0600.1.6 UN0600.1.5 / UN0600.1.9 UN0600.1.10 / UN0600.1.6 UN0600.1.11 / UN0600.1.7 UN0600.1.12 / UN0600.1.8 UN0600.1.13 / UN0600.1.9 UN0600.1.19 UN0600.1.3 UN0600.1.4 UN0600.1.7 UN0600.1.8 UN0600.2.1 UN0600.2.10 UN0600.2.11 UN0600.2.12 UN0600.2.13 UN0600.2.14 UN0600.2.15 UN0600.2.16 UN0600.2.17 UN0600.2.18 UN0600.2.19 UN0600.2.2 UN0600.2.20 UN0600.2.3 / UN0600.2.8 UN0600.2.4 UN0600.2.5 UN0600.2.6 UN0600.2.7 UN0600.2.9 |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.