Transcription Factor
| Accessions: | Q14119 (JASPAR 2024) |
| Names: | Putative transcription factor DB1, Vascular endothelial zinc finger 1, VEZF1_HUMAN, Zinc finger protein 161 |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q14119 |
| Length: | 521 |
| Pfam Domains: | 74-94 Zinc finger, C2H2 type 74-94 C2H2-type zinc finger 174-196 Zinc finger, C2H2 type 174-196 C2H2-type zinc finger 188-213 Zinc-finger double domain 202-224 Zinc finger, C2H2 type 202-224 C2H2-type zinc finger 217-242 Zinc-finger double domain 232-255 Zinc finger, C2H2 type 232-255 C2H2-type zinc finger 246-272 Zinc-finger double domain 261-283 Zinc finger, C2H2 type 261-283 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MEANWTAFLFQAHEASHHQQQAAQNSLLPLLSSAVEPPDQKPLLPIPITQKPQGAPETLK 60 61 DAIGIKKEKPKTSFVCTYCSKAFRDSYHLRRHESCHTGIKLVSRPKKTPTTVVPLISTIA 120 121 GDSSRTSLVSTIAGILSTVTTSSSGTNPSSSASTTAMPVTQSVKKPSKPVKKNHACEMCG 180 181 KAFRDVYHLNRHKLSHSDEKPFECPICNQRFKRKDRMTYHVRSHEGGITKPYTCSVCGKG 240 241 FSRPDHLSCHVKHVHSTERPFKCQTCTAAFATKDRLRTHMVRHEGKVSCNICGKLLSAAY 300 301 ITSHLKTHGQSQSINCNTCKQGISKTCMSEETSNQKQQQQQQQQQQQQQQQQQQHVTSWP 360 361 GKQVETLRLWEEAVKARKKEAANLCQTSTAATTPVTLTTPFSITSSVSSGTMSNPVTVAA 420 421 AMSMRSPVNVSSAVNITSPMNIGHPVTITSPLSMTSPLTLTTPVNLPTPVTAPVNIAHPV 480 481 TITSPMNLPTPMTLAAPLNIAMRPVESMPFLPQALPTSPPW |
| Interface Residues: | 85, 87, 88, 91, 104, 121, 122, 123, 125, 131, 151, 153, 154, 157, 160, 161, 163, 166, 170, 184, 185, 186, 187, 188, 190, 191, 192, 193, 194, 197, 212, 213, 214, 215, 216, 217, 218, 219, 220, 222, 223, 242, 243, 244, 245, 246, 247, 248, 249, 271, 272, 273, 274, 275, 278, 279, 281, 282, 299, 300, 303, 309 |
| 3D-footprint Homologues: | 5v3j_F, 7w1m_H, 6jnm_A, 3uk3_C, 8cuc_F, 7y3l_A, 1g2f_F, 5kl3_A, 1ubd_C, 5k5i_A, 2kmk_A, 6ml4_A, 6blw_A, 6u9q_A, 8ssu_A, 5kkq_D, 5ei9_F, 4m9v_C, 7y3m_I, 7ysf_A, 8ssq_A, 2lt7_A, 1tf3_A, 6e94_A, 1tf6_A, 6a57_A, 2jpa_A, 7n5w_A, 7txc_E, 1llm_D, 2drp_D, 5yel_A, 4x9j_A, 2gli_A, 1f2i_J, 2wbs_A, 8gn3_A, 5yj3_D, 8h9h_G, 5k5l_F |
| Binding Motifs: | MA1578.1 CCCCCCmytw MA1578.2 CCCCCC |
| Publications: | Dickson J, Gowher H, Strogantsev R, Gaszner M, Hair A, Felsenfeld G, West AG. VEZF1 elements mediate protection from DNA methylation. PLoS Genet : (2010). [Pubmed] |
| Related annotations: | PaperBLAST |
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