Transcription Factor
| Accessions: | P16415 (JASPAR 2024) |
| Names: | Zinc finger protein 823, Zinc finger protein ZFP-36, ZN823_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | P16415 |
| Length: | 610 |
| Pfam Domains: | 4-42 KRAB box 164-187 C2H2-type zinc finger 164-186 Zinc finger, C2H2 type 165-187 C2H2-type zinc finger 178-202 Zinc-finger double domain 191-204 C2H2-type zinc finger 192-214 Zinc finger, C2H2 type 210-229 Zinc-finger double domain 219-238 C2H2-type zinc finger 220-242 Zinc finger, C2H2 type 235-257 Zinc-finger double domain 248-270 Zinc finger, C2H2 type 248-270 C2H2-type zinc finger 248-270 C2H2-type zinc finger 263-287 Zinc-finger double domain 275-288 C2H2-type zinc finger 293-315 Zinc-finger double domain 304-326 Zinc finger, C2H2 type 304-326 C2H2-type zinc finger 304-326 C2H2-type zinc finger 318-342 Zinc-finger double domain 331-341 C2H2-type zinc finger 332-354 C2H2-type zinc finger 348-368 Zinc-finger double domain 359-382 C2H2-type zinc finger 360-382 Zinc finger, C2H2 type 360-382 C2H2-type zinc finger 375-398 Zinc-finger double domain 389-410 C2H2-type zinc finger 403-426 Zinc-finger double domain 416-426 C2H2-type zinc finger 416-438 Zinc finger, C2H2 type 416-438 C2H2-type zinc finger 430-453 Zinc-finger double domain 447-461 C2H2-type zinc finger 458-482 Zinc-finger double domain 470-493 C2H2-type zinc finger 471-493 C2H2-type zinc finger 486-510 Zinc-finger double domain 498-514 C2H2-type zinc finger 499-521 Zinc finger, C2H2 type 513-537 Zinc-finger double domain 526-537 C2H2-type zinc finger 527-549 C2H2-type zinc finger 527-549 Zinc finger, C2H2 type 542-566 Zinc-finger double domain 554-577 C2H2-type zinc finger 555-577 C2H2-type zinc finger 555-577 Zinc finger, C2H2 type 570-591 Zinc-finger double domain 582-607 C2H2-type zinc finger 583-605 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MDSVAFEDVAVNFTQEEWALLGPSQKSLYRNVMQETIRNLDCIEMKWEDQNIGDQCQNAK 60 61 RNLRSHTCEIKDDSQCGETFGQIPDSIVNKNTPRVNPCDSGECGEVVLGHSSLNCNIRVD 120 121 TGHKSCEHQEYGEKPYTHKQRGKAISHQHSFQTHERPPTGKKPFDCKECAKTFSSLGNLR 180 181 RHMAAHHGDGPYKCKLCGKAFVWPSLFHLHERTHTGEKPYECKQCSKAFPFYSSYLRHER 240 241 IHTGEKAYECKQCSKAFPDYSTYLRHERTHTGEKPYKCTQCGKAFSCYYYTRLHERTHTG 300 301 EQPYACKQCGKTFYHHTSFRRHMIRHTGDGPHKCKICGKGFDCPSSVRNHETTHTGEKPY 360 361 ECKQCGKVLSHSSSFRSHMITHTGDGPQKCKICGKAFGCPSLFQRHERTHTGEKPYQCKQ 420 421 CGKAFSLAGSLRRHEATHTGVKPYKCQCGKAFSDLSSFQNHETTHTGEKPYECKECGKAF 480 481 SCFKYLSQHKRTHTVEKPYECKTCRKAFSHFSNLKVHERIHSGEKPYECKECGKAFSWLT 540 541 CLLRHERIHTGEKPYECLQCGKAFTRSRFLRGHEKTHTGEKLYECKECGKALSSLRSLHR 600 601 HKRTHWKDTL |
| Interface Residues: | 203, 205, 206, 209, 231, 232, 233, 234, 237, 259, 261, 262, 265, 286, 287, 289, 290, 293, 315, 317, 318, 319, 320, 321, 342, 343, 345, 346, 348, 349, 352, 371, 372, 373, 374, 377, 380, 398, 399, 401, 402, 405, 427, 428, 429, 430, 433, 434, 453, 454, 455, 456, 457, 458, 459, 460, 461, 462, 463, 466, 481, 482, 483, 484, 485, 488, 491, 499, 509, 510, 511, 512, 513, 515, 516, 519, 522, 536, 537, 538, 539, 540, 541, 543, 544, 548, 565, 566, 567, 568, 569, 571, 572, 594, 595, 596, 597, 600 |
| 3D-footprint Homologues: | 6u9q_A, 5yel_A, 1ubd_C, 3uk3_C, 1llm_D, 7w1m_H, 8ssq_A, 7ysf_A, 6wmi_A, 8cuc_F, 7y3l_A, 5k5i_A, 8ssu_A, 5v3j_F, 7y3m_I, 5yj3_D, 5und_A, 4m9v_C, 1tf3_A, 6blw_A, 1tf6_A, 2i13_A, 5ei9_F, 2jpa_A, 7n5w_A, 6jnm_A, 1g2f_F, 5kkq_D, 5kl3_A, 2drp_D, 6ml4_A, 8h9h_G, 7eyi_G, 6a57_A, 2kmk_A, 4x9j_A, 1mey_C, 2gli_A, 2lt7_A, 6e94_A, 7txc_E, 2wbs_A, 1f2i_J, 8gn3_A |
| Binding Motifs: | UN0238.1 mgAGACAGAGrv UN0238.2 AGACAGAG |
| Binding Sites: | UN0238.2.18 UN0238.1.6 UN0238.1.20 UN0238.1.1 UN0238.1.10 / UN0238.1.7 UN0238.1.11 / UN0238.1.8 UN0238.1.12 UN0238.1.13 UN0238.1.14 / UN0238.1.9 UN0238.1.10 / UN0238.1.15 UN0238.1.16 UN0238.1.11 / UN0238.1.17 UN0238.1.18 UN0238.1.12 / UN0238.1.19 UN0238.1.2 UN0238.1.3 UN0238.1.4 UN0238.1.5 UN0238.1.7 UN0238.1.5 / UN0238.1.8 UN0238.1.6 / UN0238.1.9 UN0238.1.4 UN0238.1.13 UN0238.1.14 UN0238.1.15 UN0238.1.16 UN0238.1.17 UN0238.1.18 UN0238.1.19 UN0238.1.20 UN0238.2.1 / UN0238.2.10 / UN0238.2.12 / UN0238.2.19 / UN0238.2.7 UN0238.2.11 UN0238.2.13 / UN0238.2.16 UN0238.2.14 UN0238.2.15 / UN0238.2.5 UN0238.2.17 UN0238.2.2 UN0238.2.20 / UN0238.2.3 / UN0238.2.9 UN0238.2.4 UN0238.2.6 / UN0238.2.8 |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.