Transcription Factor
| Accessions: | A2A7A5 (JASPAR 2024) |
| Names: | A2A7A5_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | A2A7A5 |
| Length: | 519 |
| Pfam Domains: | 13-52 KRAB box 224-249 Zinc-finger double domain 238-260 C2H2-type zinc finger 238-260 Zinc finger, C2H2 type 252-277 Zinc-finger double domain 266-288 C2H2-type zinc finger 266-288 Zinc finger, C2H2 type 281-305 Zinc-finger double domain 294-316 C2H2-type zinc finger 294-316 Zinc finger, C2H2 type 308-333 Zinc-finger double domain 322-344 C2H2-type zinc finger 322-344 Zinc finger, C2H2 type 336-361 Zinc-finger double domain 350-372 Zinc finger, C2H2 type 367-388 Zinc-finger double domain 378-400 Zinc finger, C2H2 type 378-400 C2H2-type zinc finger 392-416 Zinc-finger double domain 406-428 Zinc finger, C2H2 type 406-428 C2H2-type zinc finger 420-444 Zinc-finger double domain 434-456 Zinc finger, C2H2 type 434-456 C2H2-type zinc finger 448-472 Zinc-finger double domain 462-484 Zinc finger, C2H2 type 462-482 C2H2-type zinc finger 476-501 Zinc-finger double domain 490-512 C2H2-type zinc finger 490-512 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MSESLVNTPQGLLTFKDVALDFSLEEWERLSFAQRTLYIDVMLENYNNLLFVENHCIRGK 60 61 YRKVLDQDSQYIVHEHMNIQEKSSKWDKLSKVLLDSPQYTPYKTYHSSLQYWNQKRLKPR 120 121 NTKEVCKYNDSVNSVSLFSTISLNQGIHMQKKKHKRNAEFEKVFVSKHKDMVKQKNTGVN 180 181 PYKCSEFHKYLTQREKLQTQQRIYHGKKPYKSSKSDKCFTHQIHLRSHQGIHTGEKPHKC 240 241 SECDKCFTHKFNLRAHQRIHTGEKLYKCSECDKCFTHKSRLNYHQRIHTGEKPHKCSECD 300 301 KCFTHKFNLRAHQIIHTGEKPHKCSECDKCFTHKFNLRAHQRIHTGEKPYKCSECDKCFT 360 361 RKFHLGIHHRIHTGEKPYKCSECDKCFTGKGSLRIHQRIHIGEKPYKCSECDKCFTGKGS 420 421 LRIHQRIHTGERPHKCSECDKCFTGKGSLRIHQRMHTGEKPYKCSECDKCFTQKSHLNIH 480 481 QGIHTGEKPYKCSECDKCFTHKSHLINHQKIHTGEKPYK |
| Interface Residues: | 249, 251, 252, 255, 266, 276, 277, 278, 279, 280, 283, 304, 305, 306, 307, 308, 310, 311, 315, 331, 332, 333, 334, 335, 336, 339, 343, 360, 361, 362, 363, 364, 367, 388, 389, 390, 391, 392, 394, 395, 398, 416, 417, 418, 419, 420, 422, 423, 425, 426, 429, 444, 445, 446, 447, 448, 450, 451, 452, 455, 457, 471, 472, 473, 474, 475, 476, 477, 478, 479, 480, 483, 500, 501, 502, 503, 504, 505, 507 |
| 3D-footprint Homologues: | 7w1m_H, 2i13_A, 1ubd_C, 2kmk_A, 5v3j_F, 1mey_C, 2drp_D, 8ssq_A, 2gli_A, 8ssu_A, 7ysf_A, 6jnm_A, 1tf3_A, 5kkq_D, 6wmi_A, 5und_A, 1tf6_A, 4x9j_A, 8gn3_A, 3uk3_C, 6blw_A, 2wbs_A, 1llm_D, 6e94_A, 8cuc_F, 6ml4_A, 7eyi_G, 5yel_A, 5ei9_F, 5k5i_A, 7y3m_I, 6a57_A, 2jpa_A, 7y3l_A, 7n5w_A, 6u9q_A, 7txc_E, 5kl3_A, 1g2f_F, 8h9h_G, 4m9v_C, 2lt7_A, 1f2i_J, 5yj3_D, 5k5l_F |
| Binding Motifs: | UN0684.1 kGCAGCArTGGhr UN0684.2 GCAGCArTGG |
| Binding Sites: | UN0684.1.1 UN0684.1.10 / UN0684.1.18 UN0684.1.11 / UN0684.1.19 UN0684.1.12 / UN0684.1.20 UN0684.1.13 UN0684.1.14 / UN0684.1.16 UN0684.1.15 UN0684.1.17 UN0684.1.18 UN0684.1.19 UN0684.1.2 UN0684.1.20 UN0684.1.3 / UN0684.1.4 UN0684.1.4 UN0684.1.5 UN0684.1.6 UN0684.1.11 / UN0684.1.7 UN0684.1.12 / UN0684.1.8 UN0684.1.14 / UN0684.1.9 UN0684.1.10 UN0684.1.13 UN0684.1.15 UN0684.1.16 UN0684.1.17 UN0684.1.3 UN0684.1.6 UN0684.1.7 UN0684.1.8 UN0684.1.9 UN0684.2.1 UN0684.2.10 / UN0684.2.11 / UN0684.2.13 / UN0684.2.14 / UN0684.2.15 / UN0684.2.16 / UN0684.2.17 / UN0684.2.18 / UN0684.2.19 / UN0684.2.3 / UN0684.2.7 UN0684.2.12 UN0684.2.2 UN0684.2.20 UN0684.2.4 UN0684.2.5 / UN0684.2.9 UN0684.2.6 UN0684.2.8 |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.