Transcription Factor
| Accessions: | 6dfy_D (3D-footprint 20231221) |
| Names: | Double homeobox protein 10, Double homeobox protein 4, DUX4_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | Q9UBX2 |
| Length: | 52 |
| Pfam Domains: | 1-51 Homeobox domain 20-50 Homeobox KN domain |
| Sequence: (in bold interface residues) | 1 TAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHP |
| Interface Residues: | 9, 10, 13, 38, 39, 41, 42, 45, 46, 49, 50 |
| 3D-footprint Homologues: | 4e0g_A, 4f43_A, 5jlw_D, 2ld5_A, 1au7_A, 1le8_A, 1ic8_B, 7q3o_C, 1ig7_A, 7xrc_C, 1e3o_C, 3cmy_A, 2h1k_B, 1jgg_B, 5flv_I, 3rkq_B, 2lkx_A, 1puf_A, 8g87_X, 1fjl_B, 5zjt_E, 4qtr_D, 3d1n_M, 2hdd_A, 7psx_B, 1b72_A, 5hod_A, 4cyc_A, 2r5y_A, 1puf_B, 6a8r_A, 4xrm_B, 3l1p_A, 1nk2_P, 1du0_A, 3a01_E, 1zq3_P, 6es3_K, 4xrs_G, 3lnq_A, 1o4x_A, 5zfz_A, 2hos_A, 6m3d_C |
| Binding Motifs: | 6dfy_CD TnATCTnATC |
| Binding Sites: | 6dfy_E 6dfy_F |
| Publications: | Aihara H, Shi K, Lee JK, Bosnakovski D, Kyba M. Comment on structural basis of DUX4/IGH-driven transactivation. Leukemia 32:2090-2092 (2018). [Pubmed] |
| Related annotations: | PaperBLAST |
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