Transcription Factor
| Accessions: | 6bz1_C (3D-footprint 20231221) |
| Names: | MEF2 CHIMERA, MEF2A_HUMAN, Myocyte-specific enhancer factor 2A, Serum response factor-like protein 1 |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Length: | 90 |
| Pfam Domains: | 9-58 SRF-type transcription factor (DNA-binding and dimerisation domain) |
| Sequence: (in bold interface residues) | 1 GRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTD 60 61 MDKVLLKYTEYSEPHESRTNTVILETLKRR |
| Interface Residues: | 2, 3, 14, 17, 18, 22, 56, 67 |
| 3D-footprint Homologues: | 1n6j_A, 1c7u_A, 7x1n_C, 1hbx_A, 1mnm_A, 7yq3_E |
| Binding Motifs: | 6bz1_CD cTAnnnntAA |
| Publications: | Lei X, Kou Y, Fu Y, Rajashekar N, Shi H, Wu F, Xu J, Luo Y, Chen L. The Cancer Mutation D83V Induces an α-Helix to β-Strand Conformation Switch in MEF2B. J Mol Biol 430:1157-1172 (2018). [Pubmed] |
| Related annotations: | PaperBLAST |
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