Transcription Factor
| Accessions: | T139289_1.02 (CISBP 1.02) |
| Names: | RUNX1, T139289_1.02; |
| Organisms: | Homo sapiens |
| Libraries: | CISBP 1.02 1 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] |
| Notes: | family:Runt |
| Length: | 480 |
| Pfam Domains: | 76-209 Runt domain 386-480 Runx inhibition domain |
| Sequence: (in bold interface residues) | 1 MASDSIFESFPSYPQCFMRECILGMNPSRDVHDASTSRRFTPPSTALSPGKMSEALPLGA 60 61 PDAGAALAGKLRSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVA 120 121 LGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVF 180 181 TNPPQVATYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSP 240 241 HHPAPTPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPAT 300 301 PISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTPV 360 361 TSGIGIGMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQFSMVG 420 421 GERSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY 480 |
| Interface Residues: | 107, 169, 197, 198, 201, 204 |
| 3D-footprint Homologues: | 3wts_A, 6vgd_D, 4l0y_A, 4l18_E, 6vg8_D |
| Binding Motifs: | M2925_1.02 ACCACA |
| Related annotations: | PaperBLAST |
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